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PMID: 10753781 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

mRNA stability in eukaryotes.

Current opinion in genetics & development ·Vol. 10 ·No. 2 ·2000-04-00 ·Pages 193-8

Mitchell P, Tollervey D

Abstract

During the past two years, the role of the proteins HuR and hnRNP D in regulated mRNA degradation in humans has become clearer, and a putative mRNA deadenylase, DAN or PARN, has been identified. In yeast, the relationship between translation and mRNA turnover is clearer, but the mRNA decapping process has turned out to be unexpectedly complex.

MeSH Terms
Animals Eukaryotic Cells/metabolism Humans RNA Stability RNA, Messenger/metabolism
Chemicals
RNA, Messenger
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Mitchell P
Institute of Cell & Molecular Biology, University of Edinburgh, Edinburgh, EH9 3JR, UK.
Tollervey D
Article Info
Journal
Current opinion in genetics & development
Abbr.
Curr Opin Genet Dev
ISSN
0959-437X
DOI
10.1016/s0959-437x(00)00063-0
Published
2000-04-00
Pages
193-8
Language
English
Region
England
NLM ID
9111375
Subset
IM
External Links
PubMed source DOI: 10.1016/s0959-437x(00)00063-0 View journal details
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