Replication fork arrest and DNA recombination.

Trends in biochemical sciences ·Vol. 25 ·No. 4 ·2000-04-00 ·Pages 173-8

Michel B

Abstract

Replication arrests are associated with genome rearrangements, which result from either homologous or non-homologous recombination. Interestingly, proteins involved in homologous recombination are able to convert an arrested replication fork into a recombination intermediate, which promotes replication restart and thus presumably prevents genome rearrangements.

MeSH Terms

DNA Helicases/genetics DNA Replication/genetics Recombination, Genetic

Chemicals

DNA Helicases

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Michel B

Laboratoire de Génétique Microbienne, Institut National de la Recherche Agronomique, 78352 Jouy en Josas Cedex, France. [email protected]

Article Info

Journal

Trends in biochemical sciences

Abbr.

Trends Biochem Sci

ISSN

0968-0004

DOI

10.1016/s0968-0004(00)01560-7

[email protected]

Published

2000-04-00

Pages

173-8

Language

English

Region

England

NLM ID

7610674

Subset

External Links

PubMed source DOI: 10.1016/s0968-0004(00)01560-7 View journal details

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Replication fork arrest and DNA recombination.

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