Late sodium current in the node of Ranvier.

Pflugers Archiv : European journal of physiology ·Vol. 357 ·No. 1-2 ·1975-00-00 ·Pages 145-8

Dubois JM, Bergman C

Abstract

Voltage clamp experiments carried out on nodes of Ranvier of myelinated fibres of Rana esculenta showed that a small fractoon of sodium channels fail to inactivate. Thus during long lasting depolarizing pulses there is a small Na-current superimposed on the leakage and potassium currents. This late Na-current appears more marked in sensory fibres than in motor ones.

MeSH Terms

Animals Electrophysiology Membrane Potentials Nerve Fibers, Myelinated/physiology Potassium Rana esculenta Ranvier's Nodes/physiology Sodium Time Factors

Chemicals

Sodium Potassium

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Dubois J M

Bergman C

References (5)

5 references, click to expand

A QUANTITATIVE DESCRIPTION OF POTASSIUM CURRENTS IN MYELINATED NERVE FIBRES OF XENOPUS LAEVIS.
J Physiol. 1963 Nov;169:424-30 PMID: 14079678
A new voltage clamp method for Ranvier nodes.
Pflugers Arch. 1969;309(2):176-92 PMID: 5815327
Potassium accumulation in the perinodal space of frog myelinated axons.
Pflugers Arch. 1975 Jul 21;358(2):111-24 PMID: 1081677
Instantaneous potassium currents in myelinated nerve fibres of Xenopus laevis.
J Physiol. 1962 Jan;160:46-53 PMID: 13894664
Specific and unspecific charges at the sodium channels of the nerve membrane.
Pflugers Arch. 1974;351(3):207-29 PMID: 4547507

Article Info

Journal

Pflugers Archiv : European journal of physiology

Abbr.

Pflugers Arch

ISSN

0031-6768

DOI

10.1007/BF00584552

Published

1975-00-00

Pages

145-8

Language

English

Region

Germany

NLM ID

0154720

Subset

External Links

PubMed source DOI: 10.1007/BF00584552 View journal details

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Late sodium current in the node of Ranvier.

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