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PMID: 10809662 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Review

Sir2 links chromatin silencing, metabolism, and aging.

Genes & development ·Vol. 14 ·No. 9 ·2000-05-01 ·Pages 1021-6

Guarente L

Abstract

暂无摘要

MeSH Terms
Aging/genetics Animals Chromatin/genetics Gene Expression Regulation Histone Deacetylases/metabolism Humans Metabolism NAD/metabolism Silent Information Regulator Proteins, Saccharomyces cerevisiae Sirtuin 1 Sirtuin 2 Sirtuins Trans-Activators/metabolism
Chemicals
Chromatin Silent Information Regulator Proteins, Saccharomyces cerevisiae Trans-Activators NAD SIR2 protein, S cerevisiae SIRT1 protein, human Sirtuin 1 Sirtuin 2 Sirtuins Histone Deacetylases
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Guarente L
Department of Biology, Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts 02139 USA. [email protected]
Article Info
Journal
Genes & development
Abbr.
Genes Dev
ISSN
0890-9369
Email
[email protected]
Published
2000-05-01
Pages
1021-6
Language
English
Region
United States
NLM ID
8711660
Subset
IM
External Links
PubMed source View journal details
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