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PMID: 1082596 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Nonsterilizing immunity in avian malaria: an antibody-independent phenomenon.

Rank RG, Weidanz WP, Bondi A

Abstract

Agammaglobulinemic chickens died with fulminating parasitemias following infection with P. gallinaceum. When rescued from otherwise fatal infection by means of chloroquine therapy, B-cell deficient chickens resisted challenge infection with the same parasite. The data suggest that nonsterilizing immunity to malaria in chickens is B-cell independent.

MeSH Terms
Agammaglobulinemia/chemically induced Animals B-Lymphocytes/immunology Bursa of Fabricius/immunology Chickens Chloroquine/therapeutic use Malaria, Avian/drug therapy,immunology Plasmodium/growth & development,immunology
Chemicals
Chloroquine
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Rank R G
Weidanz W P
Bondi A
Article Info
Journal
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)
Abbr.
Proc Soc Exp Biol Med
ISSN
0037-9727
Published
1976-02-00
Pages
257-9
Language
English
Region
United States
NLM ID
7505892
Subset
IM
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