Role of membrane structures in B-lymphocyte activation. The effect of binding anti-immunoglobulin, aggregated IgG and immune complexes.
It is shown that the binding of bivalent anti-immunoglobulin preparations to the surface immunoglobulin of murine B lymphocytes as well as the binding of aggregates of IgG or immune complexes does not lead to detectable increase in cell division in microcultures. Treating lymphocytes with immune complexes and aggregated IgG does not abolish the subsequent mitogenic response induced by LPS. The background mitosis observed in culture is inhibited with anti-immunoglobulin antibodies.
16 references, click to expand
-
Biochemical and biological characteristics of lymphocyte surface immunoglobulin.Transplant Rev. 1973;14:3-49 PMID: 4125686
-
Evidence for identity or close association of the Fc receptor of B lymphocytes and alloantigens determined by the Ir region of the H-2 complex.J Exp Med. 1974 Sep 1;140(3):779-96 PMID: 4137653
-
Development of restrictions in the expression of immunoglobulin specificities by lymphoid cells.Transplant Rev. 1970;5:19-44 PMID: 4108425
-
Induction of DNA synthesis in normal human lymphocyte cultures by antigen-antibody complexes.Clin Exp Immunol. 1969 Jan;4(1):65-82 PMID: 4182356
-
Inhibition of mitogenic stimulation of mouse lymphocytes by anti-mouse immunoglobulin antibodies. I. Mode of action.Eur J Immunol. 1974 Nov;4(11):715-22 PMID: 4214706
-
The effect of capping by anti-immunoglobulin antibody on the expression of cell surface immunoglobulin and on lymphocyte activation.Scand J Immunol. 1973;2(2):143-9 PMID: 4580486
-
Avian B lymphocyte subpopulations: origins and functional capacities.Transplant Rev. 1975;24:113-58 PMID: 49961
-
Two genes in the major histocompatibility complex control immune response.Nature. 1975 Jul 10;256(5513):103-6 PMID: 50559
-
The theory of the 'one nonspecific signal' model for b cell activation.Transplant Rev. 1975;23:49-65 PMID: 49105
-
Relationship between Fc receptors, antigen-binding sites on T and B cells, and H-2 complex-associated determinants.J Exp Med. 1975 Mar 1;141(3):547-60 PMID: 46915
-
Possible role for the Fc receptor on B lymphocytes.Nature. 1974 Jun 7;249(457):573-4 PMID: 4545851
-
Synthesis, transport, dynamics and fate of cell surface Ig and alloantigens in murine lymphocytes.Transplant Rev. 1973;14:50-75 PMID: 4542308
-
Studies on rabbit lymphocytes in vitro. 3. Proteins, RNA, and DNA synthesis by lymphocyte cultures after stimulation with phytohaemagglutinin, with staphylococcal filtrate, with antiallotype serum, and with heterologous antiserum to rabbit whole serum.J Exp Med. 1965 Oct 1;122(4):823-39 PMID: 4954762
-
Role of C'3 and Fc receptors in B-lymphocyte activation.J Exp Med. 1975 Mar 1;141(3):647-63 PMID: 1090702
-
Functional analysis of murine and human B lymphocyte subsets.Transplant Rev. 1975;24:177-236 PMID: 1096382
-
Regulation of antibody response in vitro. IX. Induction of secondary anti-hapten IgG antibody response by anti-immunoglobulin and enhancing soluble factor.J Immunol. 1975 Feb;114(2 Pt 1):585-91 PMID: 1079034
Contact
No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong
Qilu Normal University · Genelibs Bioinformatics Lab
750 Shunhua Rd, Jinan
2F, Bldg F, University Science Park
Tel: 0531-88819269
WeChat Official Account
Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.
Business Email
E-mail: [email protected]
Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2
