Mouse mononuclear cell chemotaxis: description of system.

Journal of the National Cancer Institute ·Vol. 54 ·No. 3 ·1975-03-00 ·Pages 795-9

Boetcher DA, Meltzer MS

Abstract

The mononuclear cell chemotaxis assay was adapted for use with normal mouse peritoneal cells. Mouse peritoneal macrophages responded well to endotoxinactivated mouse serum and to chemotactic factors produced by mouse spleen cell cultures stimulated with mitogens or specific antigen. The assay was quantitative, reproducible, and applicable to several mouse strains.

MeSH Terms

Animals Ascitic Fluid/cytology BCG Vaccine Cells, Cultured Chemotaxis Endotoxins/immunology Lymphocytes/immunology Male Mice/immunology Mice, Inbred C3H Mitogens/immunology Mycobacterium bovis/immunology Neutrophils/immunology Spleen/cytology

Chemicals

BCG Vaccine Endotoxins Mitogens

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Boetcher D A

Meltzer M S

Article Info

Journal

Journal of the National Cancer Institute

Abbr.

J Natl Cancer Inst

ISSN

0027-8874

Published

1975-03-00

Pages

795-9

Language

English

Region

United States

NLM ID

7503089

Subset

External Links

PubMed source View journal details

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Mouse mononuclear cell chemotaxis: description of system.

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