Lactoferrin and eosinophilic cationic protein in nasal secretions of patients with experimental rhinovirus colds, natural colds, and presumed acute community-acquired bacterial sinusitis.
To distinguish sinusitis from uncomplicated "colds," we examined lactoferrin and eosinophilic cationic protein (ECP) in nasal secretions. Lactoferrin titers were >/=1:400 in 4% of persons with uncomplicated colds and controls but in 79% of persons with sinusitis or purulent sputa. ECP levels were >200 ng/ml in 61% of persons with colds and >3,000 ng/ml in 62% of persons with sinusitis. Nasal lactoferrin helps distinguish sinusitis from colds.
15 references, click to expand
-
Comparison of fecal lactoferrin latex agglutination assay and methylene blue microscopy for detection of fecal leukocytes in Clostridium difficile-associated disease.J Clin Microbiol. 1994 May;32(5):1360-1 PMID: 8051268
-
Chronic sinusitis: risk factors for extensive disease.J Allergy Clin Immunol. 1997 Aug;100(2):185-91 PMID: 9275139
-
Chronic sinusitis. Relationship of computed tomographic findings to allergy, asthma, and eosinophilia.JAMA. 1994 Feb 2;271(5):363-7 PMID: 8283586
-
Evidence for distinct cytokine expression in allergic versus nonallergic chronic sinusitis.J Allergy Clin Immunol. 1995 Oct;96(4):537-44 PMID: 7560666
-
Acute community-acquired sinusitis.Clin Infect Dis. 1996 Dec;23(6):1209-23; quiz 1224-5 PMID: 8953061
-
Measurement of fecal lactoferrin as a marker of fecal leukocytes.J Clin Microbiol. 1992 May;30(5):1238-42 PMID: 1583125
-
Computed tomographic study of the common cold.N Engl J Med. 1994 Jan 6;330(1):25-30 PMID: 8259141
-
Eosinophil cationic protein in serum and nasal washes from wheezing infants and children.J Pediatr. 1995 Oct;127(4):558-64 PMID: 7562276
-
Occurrence of asymptomatic sinusitis in common cold and other acute ENT-infections.Rhinology. 1986 Sep;24(3):223-5 PMID: 3775189
-
Human nasal polyp epithelial basophil/mast cell and eosinophil colony-stimulating activity. The effect is T-cell-dependent.Am Rev Respir Dis. 1988 Sep;138(3):560-4 PMID: 2462380
-
Use of a lactoferrin assay in the differential diagnosis of female genital tract infections and implications for the pathophysiology of bacterial vaginosis.Sex Transm Dis. 1996 Nov-Dec;23(6):517-21 PMID: 8946639
-
Evaluation of a New Latex Agglutination Test for Fecal Lactoferrin in Travelers' Diarrhea.J Travel Med. 1994 Jun 1;1(2):68-71 PMID: 9815314
-
Estimation of nasal epithelial lining fluid using urea as a marker.J Allergy Clin Immunol. 1993 Sep;92(3):457-65 PMID: 8360397
-
Randomized controlled trial of clemastine fumarate for treatment of experimental rhinovirus colds.Clin Infect Dis. 1996 Apr;22(4):656-62 PMID: 8729205
-
Correlation of lactoferrin with neutrophilic inflammation in body fluids.Clin Diagn Lab Immunol. 1995 Nov;2(6):763-5 PMID: 8574844
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