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PMID: 1097390 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Genetic characterization of the metK locus in Escherichia coli K-12.

Journal of bacteriology ·Vol. 122 ·No. 3 ·1975-06-00 ·Pages 1144-52

Hunter JS, Greene RC, Su CH

Abstract

Three independently isolated metK mutants have been shown to have leisions lying between speB and glc near 57 min on the Escherichia coli chromosome. Two deletions result in a lack of the metC gene product but neither extends into the metK glc region. The three metK mutations are recessive to the wild-type allele carried on the KLF16 episome.

MeSH Terms
Arginine/metabolism Chromosome Mapping Crosses, Genetic Cystathionine beta-Synthase/biosynthesis Cystathionine gamma-Lyase/biosynthesis Diploidy Escherichia coli/enzymology,metabolism Ethionine/metabolism Genetic Linkage Haploidy Lysine/metabolism Methionine/biosynthesis,metabolism Methionine Adenosyltransferase/biosynthesis Mutation Ornithine/metabolism Serine/metabolism Transduction, Genetic Transferases/biosynthesis
Chemicals
Serine Arginine Methionine Ornithine Transferases Methionine Adenosyltransferase Cystathionine beta-Synthase Cystathionine gamma-Lyase Lysine Ethionine
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Hunter J S
Greene R C
Su C H
References (29)
29 references, click to expand
  1. THE EFFECT OF ACRIDINE DYES ON MATING TYPE FACTORS IN ESCHERICHIA COLI.
    Proc Natl Acad Sci U S A. 1960 Jan;46(1):57-64 PMID: 16590598
  2. TOPOGRAPHY OF COTRANSDUCIBLE ARGININE MUTATIONS IN ESCHERICHIA COLI K-12.
    Genetics. 1965 Feb;51:167-79 PMID: 14292146
  3. IMPROVED METHOD FOR THE ISOLATION OF THYMINE-REQUIRING MUTANTS OF ESCHERICHIA COLI.
    J Bacteriol. 1965 Aug;90:554-5 PMID: 14329476
  4. Mutants of Escherichia coli requiring methionine or vitamin B12.
    J Bacteriol. 1950 Jul;60(1):17-28 PMID: 15436457
  5. MEASUREMENT OF LOW ENERGY BETA-EMITTERS IN AQUEOUS SOLUTION BY LIQUID SCINTILLATION COUNTING OF EMULSIONS.
    Anal Chem. 1965 Jun;37:854-7 PMID: 14326976
  6. Escherichia coli K-12 F-prime factors, old and new.
    Bacteriol Rev. 1972 Dec;36(4):587-607 PMID: 4568765
  7. Properties of metK mutants of Escherichia coli K-12.
    J Bacteriol. 1973 Jul;115(1):57-67 PMID: 4577753
  8. S-Adenosylmethionine synthetase deficient mutants of Escherichia coli K-12 with impaired control of methionine biosynthesis.
    Biochem Biophys Res Commun. 1970 Mar 27;38(6):1120-6 PMID: 4908544
  9. Regulation of S-adenosylmethionine synthetase in Escherichia coli.
    J Bacteriol. 1970 Nov;104(2):734-47 PMID: 4923071
  10. Mapping of the structural genes of the three aspartokinases and of the two homoserine dehydrogenases of Escherichia coli K-12.
    J Bacteriol. 1974 Jan;117(1):133-43 PMID: 4148765
  11. Biochemical and physiological properties of methionyl-sRNA synthetase mutants of Salmonella typhimurium.
    J Gen Microbiol. 1971 Jan;65(1):5-21 PMID: 4326110
  12. The regulation of methionine and s-adenosylmethionine biosynthesis and utilization in mutants of Salmonella typhimurium with defects in s-adenosylmethionine synthetase.
    Mol Gen Genet. 1974;131(3):263-73 PMID: 4612331
  13. Mass screening for mutants with altered DNases by microassay techniques.
    Methods Enzymol. 1974;29:180-93 PMID: 4604728
  14. Mechanism of repression of methionine biosynthesis in Escherichia coli. I. The role of methionine, s-adenosylmethionine, and methionyl-transfer ribonucleic acid in repression.
    Mol Gen Genet. 1973 Jul 16;123(4):299-324 PMID: 4580267
  15. Excretion of enterochelin by exbA and exbB mutants of Escherichia coli.
    J Bacteriol. 1973 Jun;114(3):1225-30 PMID: 4576403
  16. S-adenosylmethionine synthetase in methionine regulatory mutants of Salmonella typhimurium.
    Mol Gen Genet. 1973 Oct 16;126(1):7-18 PMID: 4591373
  17. Mapping of genes involved in the synthesis of spermidine in Escherichia coli.
    Mol Gen Genet. 1972;119(1):1-9 PMID: 4564714
  18. Prophage lambda at unusual chromosomal locations. I. Location of the secondary attachment sites and the properties of the lysogens.
    J Mol Biol. 1972 Feb 14;63(3):483-503 PMID: 4552408
  19. P1 transduction: formation of heterogenotes upon cotransduction of bacterial genes with a P2 prophage.
    Virology. 1972 Jan;47(1):76-93 PMID: 4550792
  20. A functional analysis of the rel gene in Escherichia coli.
    J Mol Biol. 1969 Oct 28;45(2):195-203 PMID: 4904406
  21. [Physiology and genetics of isocitritase and the malate synthases of Escherichia coli].
    Eur J Biochem. 1968 Jun;5(1):81-90 PMID: 4874804
  22. Regulation of methionine synthesis in Salmonella typhimurium: mutants resistant to inhibition by analogues of methionine.
    Genetics. 1968 Apr;58(4):473-92 PMID: 4879382
  23. Enzymatic synthesis of homocysteine or methionine directly from O-succinyl-homoserine.
    Biochim Biophys Acta. 1967 Mar 15;132(2):400-5 PMID: 5340123
  24. Genetic studies on bacteriophage P1.
    Virology. 1968 Dec;36(4):564-74 PMID: 4881411
  25. Synthesis of the succinic ester of homoserine, a new intermediate in the bacterial biosynthesis of methionine.
    Biochemistry. 1965 Jul;4(7):1370-5 PMID: 5323138
  26. Regulation of methionine biosynthesis in Escherichia coli: mapping of the metJ locus and properties of a metJ plus-metJ minus diploid.
    Proc Natl Acad Sci U S A. 1971 Feb;68(2):367-71 PMID: 5277087
  27. Dominance of the wild-type alleles of methionine regulatory genes in Salmonella typhimurium.
    J Gen Microbiol. 1970 Sep;63(1):95-109 PMID: 5500029
  28. Suppression of methionyl transfer RNA synthetase mutants of Salmonella typhimurium by methionine regulatory mutations.
    J Gen Microbiol. 1970 Sep;63(1):121-31 PMID: 5500020
  29. Cystathionine gamma-synthase. A pyridoxal phosphate enzyme catalyzing rapid exchanges of beta and alpha hydrogen atoms in amino acids.
    J Biol Chem. 1969 Nov 25;244(22):6217-27 PMID: 5350958
Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
Published
1975-06-00
Pages
1144-52
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC246170
Subset
IM
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