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PMID: 1101030 Published · ppublish English Journal Article

Tetracycline-sensitive mutants of the F-like R factors R100 and R100-1.

Molecular & general genetics : MGG ·Vol. 137 ·No. 1 ·1975-00-00 ·Pages 85-88

Foster TJ

Abstract

The majority of tetracycline-sensitive (Tets) mutants of R100 and R100-1 are multisite (deletion) mutants. About 50% of these are also transfer-deficient, indicating that the Tetr locus is closely linked to the transfer genes. Tet(s) mutants with single-site lesions are also described.

MeSH Terms
Chromosome Deletion Chromosomes, Bacterial Conjugation, Genetic Drug Resistance, Microbial Escherichia coli/drug effects,physiology F Factor Mutation R Factors Tetracycline/pharmacology
Chemicals
Tetracycline
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Foster T J
References (4)
4 references, click to expand
  1. Electron microscope heteroduplex studies of sequence relations among plasmids of Escherichia coli. II. Structure of drug resistance (R) factors and F factors.
    J Mol Biol. 1973 Apr 5;75(2):235-55 PMID: 4580676
  2. Deletion map of the chloramphenicol resistance region of R1 and R100-1.
    J Bacteriol. 1973 Nov;116(2):1062-3 PMID: 4583232
  3. Resistance of Escherichia coli to tetracyclines. Changes in permeability to tetracyclines in Escherichia coli bearing transferable resistance factors.
    Biochem J. 1967 Oct;105(1):371-8 PMID: 4861886
  4. Recombination and complementation between R factors in Escheichia coli K 12.
    Genet Res. 1971 Dec;18(3):287-97 PMID: 4945740
Article Info
Journal
Molecular & general genetics : MGG
Abbr.
Mol Gen Genet
ISSN
0026-8925
Published
1975-00-00
Pages
85-88
Language
English
Region
Germany
NLM ID
0125036
Subset
IM
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