Home LiteratureArticle Details
PMID: 1104479 Published · ppublish English Comparative Study Journal Article

Adherence of enteropathogenic Escherichia coli to intestinal epithelium in vivo.

Infection and immunity ·Vol. 12 ·No. 4 ·1975-10-00 ·Pages 866-80

Hohmann A, Wilson MR

Abstract

Two porcine strains of enteropathogenic Escherichia coli, one possessing K88 antigen and one lacking K88, were orally inoculated into conventional neonatal piglets. Athough both strains caused severe diarrhea, only the K88-possessing strain was able to proliferate in the anterior small intestine. Both K88-possessing and K88-lacking strains were found in large numbers in the posterior small intestine and, using fluorescent antibodies and scanning and transmission electron microscopy, were found adhering to the epitheial surface in these regions. The presence of an unusual surface structure on the bacterial cell of the K88-lacking strain was described.

MeSH Terms
Administration, Oral Animals Antigens, Bacterial/administration & dosage Cell Adhesion Escherichia coli/isolation & purification,physiology,ultrastructure Fluorescent Antibody Technique Immune Sera/isolation & purification Intestinal Mucosa/microbiology,ultrastructure Rabbits Swine
Chemicals
Antigens, Bacterial Immune Sera
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Hohmann A
Wilson M R
References (23)
23 references, click to expand
  1. Pathogenesis of neonatal enteric colibacillosis of pigs.
    J Am Vet Med Assoc. 1972 Feb 15;160(4):574-82 PMID: 4555389
  2. Small intestinal lesions of transmissible gastroenteritis in gnotobiotic pigs: a scanning electron microscopic study.
    Am J Vet Res. 1973 Oct;34(10):1239-45 PMID: 4748236
  3. Observations on the pathogenic properties of the K88, Hly and Ent plasmids of Escherichia coli with particular reference to porcine diarrhoea.
    J Med Microbiol. 1971 Nov;4(4):467-85 PMID: 4944321
  4. Enteric colibacillosis in the newborn pig: problems of diagnosis and control.
    J Am Vet Med Assoc. 1969 Dec 15;155(12):1853-9 PMID: 4904961
  5. Enteric colibacillosis in gnotobiotic swine: a fluorescence microscopic study.
    Am J Vet Res. 1970 Jul;31(7):1147-57 PMID: 4915057
  6. The location of Escherichia coli in the pig intestine.
    J Med Microbiol. 1970 May;3(2):333-40 PMID: 4916321
  7. The production of oedema disease and diarrhoea in weaned pigs by the oral administration of Escherichia coli: factors that influence the course of the experimental disease.
    J Med Microbiol. 1968 Aug;1(1):45-59 PMID: 4918220
  8. Studies on Escherichia coli enterotoxin.
    J Pathol Bacteriol. 1967 Apr;93(2):531-43 PMID: 4861401
  9. Observations by the ligated intestinal segment and oral inoculation methods on Escherichia coli infections in pigs, calves, lambs and rabbits.
    J Pathol Bacteriol. 1967 Apr;93(2):499-529 PMID: 4861400
  10. Enteric colibacillosis in swine.
    J Am Vet Med Assoc. 1968 Dec 15;153(12):1590-606 PMID: 4881913
  11. The structure, function, synthesis and genetic control of bacterial pili and a molecular model for DNA and RNA transport in gram negative bacteria.
    Trans N Y Acad Sci. 1965 Jun;27(8):1003-54 PMID: 5318403
  12. Motility as a virulence factor for Vibrio cholerae.
    Infect Immun. 1975 May;11(5):890-7 PMID: 1091563
  13. OBSERVATIONS ON THE ALIMENTARY TRACT AND ITS BACTERIAL FLORA IN HEALTHY AND DISEASED PIGS.
    J Pathol Bacteriol. 1963 Oct;86:387-412 PMID: 14068948
  14. Non-flagellar filamentous appendages (fimbriae) and haemagglutinating activity in Bacterium coli.
    J Pathol Bacteriol. 1955 Oct;70(2):335-48 PMID: 13295908
  15. Vacuolated villous epithelium of the small intestine of young pigs.
    Vet Pathol. 1972;9(1):3-21 PMID: 4135828
  16. Agglutination of trypsinized sheep erythrocytes by the pili of Corynebacterium renale.
    Infect Immun. 1974 Dec;10(6):1426-32 PMID: 4373397
  17. The significance of proliferation and enterotoxin production by Escherichia coli in the intestine of gnotobiotic pigs.
    Can J Comp Med. 1972 Apr;36(2):150-9 PMID: 4259929
  18. The association of K88 antigen with haemagglutinating activity in porcine strains of Escherichia coli.
    J Gen Microbiol. 1974 Sep;84(1):135-44 PMID: 4612097
  19. Immunity to Escherichia coli in pigs: adhesion of enteropathogenic Escherichia coli to isolated intestinal epithelial cells.
    Infect Immun. 1974 Oct;10(4):776-82 PMID: 4609910
  20. Role of the K88 antigen in the pathogenesis of neonatal diarrhea caused by Escherichia coli in piglets.
    Infect Immun. 1972 Dec;6(6):918-27 PMID: 4629393
  21. Protection of pigs against neonatal enteric colibacillosis with colostrum and milk from orally vaccinated sows.
    Am J Vet Res. 1974 Mar;35(3):331-8 PMID: 4594741
  22. Association of Escherichia coli with the small intestinal epithelium. I. Comparison of enteropathogenic and nonenteropathogenic porcine strains in pigs.
    Infect Immun. 1972 Apr;5(4):595-605 PMID: 4564680
  23. Protection against enteric disease caused by Escherichia coli--a model for vaccination with a virulence determinant?
    Nature. 1973 Apr 20;242(5399):531-2 PMID: 4573477
Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/iai.12.4.866-880.1975
Published
1975-10-00
Pages
866-80
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC415368
Subset
IM
External Links
PubMed source DOI: 10.1128/iai.12.4.866-880.1975 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2