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PMID: 11053402 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Cholic acid is accumulated spontaneously, driven by membrane deltapH, in many lactobacilli.

Journal of bacteriology ·Vol. 182 ·No. 22 ·2000-11-00 ·Pages 6525-8

Kurdi P, van Veen HW, Tanaka H, Mierau I, Konings WN, Tannock GW, Tomita F, Yokota A

Abstract

Many lactobacilli from various origins were found to apparently lack cholic acid extrusion activity. Cholic acid was accumulated spontaneously, driven by the transmembrane proton gradient. Accumulation is a newly identified kind of interaction between intestinal microbes and unconjugated bile acids and is different from extrusion and modification, which have been described previously.

MeSH Terms
Biological Transport Cholic Acid/metabolism Hydrogen-Ion Concentration Lactobacillus/metabolism
Chemicals
Cholic Acid
Authors & Affiliations
8 authors, click to expand affiliations / ORCID
Kurdi P
Laboratory of Applied Microbiology, Research Group of Molecular Bioscience, Division of Applied Bioscience, Graduate School of Agriculture, Hokkaido University, Sapporo 060-8589, Japan.
van Veen H W
Tanaka H
Mierau I
Konings W N
Tannock G W
Tomita F
Yokota A
References (11)
11 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/JB.182.22.6525-6528.2000
Published
2000-11-00
Pages
6525-8
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC94804
Subset
IM
External Links
PubMed source DOI: 10.1128/JB.182.22.6525-6528.2000 PMC Full Text View journal details
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