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PMID: 1108198 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

BCG inhibition of murine leudemia: local suppression and systemic tumor immunity require different doses.

Science (New York, N.Y.) ·Vol. 191 ·No. 4224 ·1976-01-23 ·Pages 299-301

Bartlett GL, Purnell DM, Kreider JW

Abstract

The quantitative relationship between bacillus Calmette-Guérin (BCG) and tumor cells which are optimal for suppressing the growth of tumor cells in BCG-tumor cell mixtures are detrimental to the development of a sustained, systemic tumor rejection immunity in the LSTRA murine leukemia.

MeSH Terms

Adjuvants, Immunologic Animals BCG Vaccine Immunization Leukemia, Experimental/immunology,prevention & control Male Mice Mice, Inbred Strains Mycobacterium bovis/immunology Neoplasm Transplantation

Chemicals

Adjuvants, Immunologic BCG Vaccine

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Bartlett G L

Purnell D M

Kreider J W

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.1108198

Published

1976-01-23

Pages

299-301

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.1108198 View journal details

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BCG inhibition of murine leudemia: local suppression and systemic tumor immunity require different doses.

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