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PMID: 11086249 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

The flow patterns within the impeller passages of a centrifugal blood pump model.

Medical engineering & physics ·Vol. 22 ·No. 6 ·2000-07-00 ·页码 381-93

Yu SC, Ng BT, Chan WK, Chua LP

Abstract

The effects of impeller geometry on the performance of a centrifugal blood pump model [the MSCBP design of Akamatsu and Tsukiya (The Seventh Asian Congress of Fluid Mechanics (1997), 7-10) at a 1:1 scale] have been investigated both experimentally and computationally. Four impeller designs were tested for pump hydraulic performance at the operating point (i.e. 2000 rpm), using blood analog as the working fluid. Each impeller has seven blades with different configurations including the radial straight blade and backward swept blade designs. The results show that both designs can achieve a stable head of about 100 mm Hg at the operating point. Subsequent investigations involved the visualization of the relative flow field within the impeller passages via the image de-rotation system coupled with a 2.5 W argon ion laser. Flow structures in all sectors of each impeller were examined and discussed. To further quantify the possible effects of blade geometry to thrombus formation and hemolysis, computational fluid dynamics (CFD) was used to simulate a simplified two-dimensional blade-to-blade flow analysis so as to estimate the shear stress levels. The results indicate that the stress levels found within the blade passages are generally below the threshold level of 150 N/m(2) for extensive erythrocyte damage to occur. There are some localized regions near the leading edge of the blades where the stress levels are 60% above the threshold level. However, given such a short residence time for the fluid particles to go through these high shear stress regions, their effects appear to be insignificant.

MeSH 主题词
Blood Flow Velocity/physiology Blood Substitutes Equipment Design/methods,standards Heart, Artificial/adverse effects,standards Heart-Assist Devices/adverse effects,standards Hemolysis/physiology Hemorheology/instrumentation,methods Humans Lasers Microspheres Models, Cardiovascular Stress, Mechanical Thrombosis/prevention & control
化学物质
Blood Substitutes
作者与单位
共 4 位作者,点击展开单位 / ORCID
Yu S C
Nanyang Technological University, Thermal and Fluids Engineering Division, School of Mechanical and Production Engineering, 639798, Singapore. [email protected]
Ng B T
Chan W K
Chua L P
Article Info
Journal
Medical engineering & physics
Abbr.
Med Eng Phys
ISSN
1350-4533
Corresponding email
Published
2000-07-00
页码
381-93
Language
English
Country/Region
England
NLM ID
9422753
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