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PMID: 11173292 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

Deoxyxylulose phosphate pathway to terpenoids.

Trends in plant science ·Vol. 6 ·No. 2 ·2001-02-00 ·Pages 78-84

Eisenreich W, Rohdich F, Bacher A

Abstract

Recently, a mevalonate-independent pathway was discovered in bacteria and plants that leads to the formation of isopentenyl diphosphate and dimethylallyl diphosphate, the two basic precursors of isoprenoids. Although many details of the widely distributed pathway are unknown, some intermediates, mechanisms, enzymes and genes of this novel route have been identified. Information on this pathway could provide the basis for the development of new antibiotics, herbicides and antimalarials.

MeSH Terms
Diphosphates/metabolism Enzymes/metabolism Genes, Bacterial Genes, Plant Hemiterpenes Mevalonic Acid/metabolism Organophosphorus Compounds/metabolism Terpenes/metabolism Xylulose/analogs & derivatives,metabolism
Chemicals
Diphosphates Enzymes Hemiterpenes Organophosphorus Compounds Terpenes isopentenyl pyrophosphate Xylulose 1-deoxy-2-pentulose Mevalonic Acid
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Eisenreich W
Lehrstuhl für Organische Chemie und Biochemie, Technische Universität München, Lichtenbergstrasse 4, D-85747, Garching, Germany. [email protected]
Rohdich F
Bacher A
Article Info
Journal
Trends in plant science
Abbr.
Trends Plant Sci
ISSN
1360-1385
Published
2001-02-00
Pages
78-84
Language
English
Region
England
NLM ID
9890299
Subset
IM
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