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PMID: 11208869 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

Differentiation of T regulatory cells by immature dendritic cells.

The Journal of experimental medicine ·Vol. 193 ·No. 2 ·2001-01-15 ·Pages F5-9

Roncarolo MG, Levings MK, Traversari C

Abstract

暂无摘要

MeSH Terms
Cell Communication Cell Differentiation Dendritic Cells/classification,cytology,immunology Humans Immune Tolerance Inflammation/immunology Self Tolerance T-Lymphocytes/cytology,immunology
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Roncarolo M G
San Raffaele Telethon Institute for Gene Therapy, Milan, Italy. [email protected]
Levings M K
Traversari C
References (43)
43 references, click to expand
  1. T suppressor lymphocytes inhibit NF-kappa B-mediated transcription of CD86 gene in APC.
    J Immunol. 1999 Dec 15;163(12):6386-92 PMID: 10586028
  2. Dendritic cells and the control of immunity.
    Nature. 1998 Mar 19;392(6673):245-52 PMID: 9521319
  3. The third function of the thymus.
    Immunol Today. 2000 Feb;21(2):95-9 PMID: 10652468
  4. The induction of tolerance by dendritic cells that have captured apoptotic cells.
    J Exp Med. 2000 Feb 7;191(3):411-6 PMID: 10662786
  5. A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes.
    J Exp Med. 2000 Feb 7;191(3):435-44 PMID: 10662789
  6. The control of T cell responses by dendritic cell subsets.
    Curr Opin Immunol. 2000 Feb;12(1):114-21 PMID: 10679408
  7. Type I IFN modulates innate and specific antiviral immunity.
    J Immunol. 2000 Apr 15;164(8):4220-8 PMID: 10754318
  8. Transport of peptide-MHC class II complexes in developing dendritic cells.
    Science. 2000 Apr 21;288(5465):522-7 PMID: 10775112
  9. CC chemokine receptor-7 on dendritic cells is induced after interaction with apoptotic tumor cells: critical role in migration from the tumor site to draining lymph nodes.
    Cancer Res. 2000 Apr 15;60(8):2209-17 PMID: 10786686
  10. Induction of xenoreactive CD4+ T-cell anergy by suppressor CD8+CD28- T cells.
    Transplantation. 2000 Apr 15;69(7):1304-10 PMID: 10798745
  11. Regulatory T cells in autoimmmunity*.
    Annu Rev Immunol. 2000;18:423-49 PMID: 10837065
  12. Immunobiology of dendritic cells.
    Annu Rev Immunol. 2000;18:767-811 PMID: 10837075
  13. Natural interferon alpha/beta-producing cells link innate and adaptive immunity.
    J Exp Med. 2000 Jul 17;192(2):219-26 PMID: 10899908
  14. Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation.
    J Exp Med. 2000 Jul 17;192(2):295-302 PMID: 10899916
  15. Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.
    J Exp Med. 2000 Jul 17;192(2):303-10 PMID: 10899917
  16. Human monocyte-derived dendritic cells induce naive T cell differentiation into T helper cell type 2 (Th2) or Th1/Th2 effectors. Role of stimulator/responder ratio.
    J Exp Med. 2000 Aug 7;192(3):405-12 PMID: 10934228
  17. Dendritic cells and prospects for transplantation tolerance.
    Curr Opin Immunol. 2000 Oct;12(5):528-35 PMID: 11007355
  18. Dendritic cells: multi-lineal and multi-functional.
    Immunol Today. 2000 Sep;21(9):431-3 PMID: 11012244
  19. Monocyte-derived CD1a+ and CD1a- dendritic cell subsets differ in their cytokine production profiles, susceptibilities to transfection, and capacities to direct Th cell differentiation.
    J Immunol. 2000 Oct 1;165(7):3584-91 PMID: 11034359
  20. T regulatory cells 1 inhibit a Th2-specific response in vivo.
    J Immunol. 2000 Nov 1;165(9):4848-53 PMID: 11046008
  21. Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells.
    J Exp Med. 2000 Nov 6;192(9):1213-22 PMID: 11067871
  22. The role of different subsets of T regulatory cells in controlling autoimmunity.
    Curr Opin Immunol. 2000 Dec;12(6):676-83 PMID: 11102772
  23. Plasmacytoid dendritic cells activated by influenza virus and CD40L drive a potent TH1 polarization.
    Nat Immunol. 2000 Oct;1(4):305-10 PMID: 11017101
  24. Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells.
    J Exp Med. 2001 Jan 15;193(2):233-8 PMID: 11208863
  25. Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo.
    J Exp Med. 1987 Feb 1;165(2):302-19 PMID: 3029267
  26. Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes.
    Nature. 1988 Jun 23;333(6175):742-6 PMID: 3260350
  27. Peripheral selection of the T cell repertoire.
    Science. 1991 Mar 8;251(4998):1225-8 PMID: 1900951
  28. Human hematopoietic cells and thymic epithelial cells induce tolerance via different mechanisms in the SCID-hu mouse thymus.
    J Exp Med. 1992 Apr 1;175(4):1033-43 PMID: 1348080
  29. Interleukin-10.
    Annu Rev Immunol. 1993;11:165-90 PMID: 8386517
  30. A subclass of dendritic cells kills CD4 T cells via Fas/Fas-ligand-induced apoptosis.
    J Exp Med. 1996 Apr 1;183(4):1789-96 PMID: 8666935
  31. In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha.
    J Immunol. 1996 Jul 15;157(2):798-805 PMID: 8752931
  32. A subclass of dendritic cells regulates the response of naive CD8 T cells by limiting their IL-2 production.
    J Immunol. 1996 Nov 1;157(9):3819-27 PMID: 8892611
  33. A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis.
    Nature. 1997 Oct 16;389(6652):737-42 PMID: 9338786
  34. Induction of tolerance by IL-10-treated dendritic cells.
    J Immunol. 1997 Nov 15;159(10):4772-80 PMID: 9366401
  35. CD4+CD25+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells.
    J Immunol. 1998 Feb 1;160(3):1212-8 PMID: 9570536
  36. Efficient presentation of phagocytosed cellular fragments on the major histocompatibility complex class II products of dendritic cells.
    J Exp Med. 1998 Dec 7;188(11):2163-73 PMID: 9841929
  37. Reciprocal control of T helper cell and dendritic cell differentiation.
    Science. 1999 Feb 19;283(5405):1183-6 PMID: 10024247
  38. Interleukin-10-treated human dendritic cells induce a melanoma-antigen-specific anergy in CD8(+) T cells resulting in a failure to lyse tumor cells.
    Blood. 1999 Mar 1;93(5):1634-42 PMID: 10029592
  39. TGF-beta 1 prevents the noncognate maturation of human dendritic Langerhans cells.
    J Immunol. 1999 Apr 15;162(8):4567-75 PMID: 10201996
  40. The nature of the principal type 1 interferon-producing cells in human blood.
    Science. 1999 Jun 11;284(5421):1835-7 PMID: 10364556
  41. Viruses, host responses, and autoimmunity.
    Immunol Rev. 1999 Jun;169:241-53 PMID: 10450521
  42. Modulating dendritic cells to optimize mucosal immunization protocols.
    J Immunol. 1999 Oct 1;163(7):3668-75 PMID: 10490961
  43. TGF-beta1 regulation of dendritic cells.
    Microbes Infect. 1999 Dec;1(15):1283-90 PMID: 10611756
Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
DOI
10.1084/jem.193.2.f5
Email
[email protected]
Published
2001-01-15
Pages
F5-9
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2193342
Subset
IM
Grants
Telethon · TGT00Z04 · Italy
Telethon · TGT06S01 · Italy
External Links
PubMed source DOI: 10.1084/jem.193.2.f5 PMC Full Text View journal details
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