Home LiteratureArticle Details

PMID: 1123254 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Chronic proliferative arthritis of mice induced by Mycoplasma arthritidis: demonstration of a cell-mediated immune response to mycoplasma antigens in vitro.

Infection and immunity ·Vol. 11 ·No. 5 ·1975-05-00 ·Pages 1159-61

Cole BC, Golightly-Rowland L, Ward JR

Abstract

Lymphocytes taken from mice chronically infected with Mycoplasma arthritidis exhibited a significant blastogenic response as measured by (3H)thymidine uptake when exposed in vitro to M. arthritidis antigens. The lymphocytes taken from 9 of 12 control mice of similar age exhibited an inhibition of (3H)thymidine uptake when exposed to M. arthritidis antigens.

MeSH Terms

Animals Antigens, Bacterial Arthritis/immunology,microbiology Immunity, Cellular Lymphocyte Activation Mice Mycoplasma/immunology Mycoplasma Infections/immunology Thymidine/metabolism Tritium

Chemicals

Antigens, Bacterial Tritium Thymidine

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Cole B C

Golightly-Rowland L

Ward J R

References (14)

14 references, click to expand

Rheumatoid arthritis--an infection?
Arthritis Rheum. 1963 Apr;6:159-65 PMID: 13963071
Detection and characterization of defective mycoplasmacidal antibody produced by rodents against Mycoplasma arthritidis.
Infect Immun. 1973 Aug;8(2):199-207 PMID: 4125266
Studies of PPLO infection. V. Inhibition of lymphocyte mitosis and antibody formation by mycoplasmal extracts.
J Exp Med. 1969 Jun 1;129(6):1163-81 PMID: 4306341
Mycoplasma-associated immunosuppression: effect on hemagglutinin response to common antigens in rabbits.
Infect Immun. 1974 Feb;9(2):410-5 PMID: 4593344
Interaction of Mycoplasma arthritidis and other mycoplasmas with murine peritoneal macrophages.
Infect Immun. 1973 May;7(5):691-9 PMID: 4587519
The immunosuppressive effect of mycoplasma infection. I. Effect on the humoral and cellular response.
Immunology. 1972 Apr;22(4):695-702 PMID: 5016239
Schistosomal egg antigen-induced lymphocyte blastogenesis in experimental murine Schistosoma mansoni infection.
J Immunol. 1971 Nov;107(5):1477-80 PMID: 5000731
The interaction in vitro between polymorphonuclear leukocytes and mycoplasma.
J Exp Med. 1971 Dec 1;134(6):1417-30 PMID: 4942406
Immunological responses of the rat to Mycoplasma arthritidis.
J Bacteriol. 1969 Jun;98(3):930-7 PMID: 5305935
Chronic proliferative arthritis of mice induced by Mycoplasma arthritidis. II. Serological responses of the lost and effect of vaccines.
Infect Immun. 1971 Oct;4(4):431-40 PMID: 5154890
Chronic proliferative arthritis of mice induced by Mycoplasma arthritidis. I. Induction of disease and histopathological characteristics.
Infect Immun. 1971 Oct;4(4):344-55 PMID: 5154887
Mixed lymphocyte blastogenesis in response to multiple histocompatibility antigens.
J Immunol. 1969 Jan;102(1):107-16 PMID: 5765450
Some properties of the inhibitor(s) of lymphocyte mitosis derived from Mycoplasma.
J Bacteriol. 1968 Jun;95(6):2418-9 PMID: 5669914
Reversible inhibition of mitosis in lymphocyte cultures by non-viable Mycoplasma.
Proc Soc Exp Biol Med. 1966 Dec;123(3):790-5 PMID: 5959021

Article Info

Journal

Infection and immunity

Abbr.

Infect Immun

ISSN

0019-9567

DOI

10.1128/iai.11.5.1159-1161.1975

Published

1975-05-00

Pages

1159-61

Language

English

Region

United States

NLM ID

0246127

PMCID

PMC415192

Subset

External Links

PubMed source DOI: 10.1128/iai.11.5.1159-1161.1975 PMC Full Text View journal details

Analysis Services

Chronic proliferative arthritis of mice induced by Mycoplasma arthritidis: demonstration of a cell-mediated immune response to mycoplasma antigens in vitro.

Contact

WeChat Official Account