Nonallelic behavior of rabbit variable-region allotypes.
Group a allotypes not detected by qualitative typing or anticipated from breeding data (latent allotypes) were detected at low levels in 50% of normal rabbit sera tested. The latent allotypes, which were serologically identical to allotypes of pooled IgG, were detected in sera from rabbits with all possible combinations of group a allotypes and their occurrence in individual rabbits was transitory and sporadic. These findings give reason to question the assumption that the synthesis of immunoglobulin allotypes is directed by allelic structural genes.
9 references, click to expand
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Expression of IgG allotypes in human lymphoid tumor lines serially transplantable in the neonatal Syrian hamster.J Immunol. 1974 Dec;113(6):1984-91 PMID: 4214867
-
Human immunoglobulins: classes, subclasses, genetic variants, and idiotypes.Adv Immunol. 1973;16:1-59 PMID: 4125921
-
Congenic mouse strains: the expression of a hidden immunoglobulin allotype in a congenic partner strain of BALB-c mice.J Exp Med. 1974 Mar 1;139(3):512-27 PMID: 4130242
-
A rabbit with the allotypic phenotype: ala2a3 b4b5b6.J Immunol. 1974 Oct;113(4):1313-8 PMID: 4137513
-
Identification and genetic control of the f4 and f5 rabbit gamma-A immunoglobulin allotypes. Phenogroups at the f locus.J Immunol. 1969 Oct;103(4):662-7 PMID: 4186912
-
Immunoglobulin allotypic specificities in mixed leucocyte cultures.Immunology. 1973 Jun;24(6):1041-9 PMID: 4268728
-
Detection of idiotypic cross-reactions among streptococcal antisera from related rabbits.J Exp Med. 1973 Sep 1;138(3):522-37 PMID: 4727913
-
Quantitative determination of allotypic and idiotypic markers with antisera coupled to N-hydroxysuccinimide-activated sepharose.J Immunol. 1975 Jan;114(1 Pt 1):51-4 PMID: 1167562
-
A simplification of the radioactive antigen-binding test by a double label technique.J Immunol. 1971 Sep;107(3):910-1 PMID: 5572096
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