Regulation of the p53 pathway by Ras, the plot thickens.

Animals Cell Cycle/physiology Cell Line Gene Expression Regulation, Neoplastic Genes, Tumor Suppressor Humans Neoplasm Proteins/genetics,metabolism Nuclear Proteins Promyelocytic Leukemia Protein Proto-Oncogene Proteins/biosynthesis Proto-Oncogene Proteins c-mdm2 Signal Transduction Transcription Factors/genetics,metabolism Tumor Cells, Cultured Tumor Suppressor Protein p53/genetics,metabolism Tumor Suppressor Proteins ras Proteins/physiology

DMTF1 protein, human Neoplasm Proteins Nuclear Proteins Promyelocytic Leukemia Protein Proto-Oncogene Proteins Transcription Factors Tumor Suppressor Protein p53 Tumor Suppressor Proteins PML protein, human MDM2 protein, human Proto-Oncogene Proteins c-mdm2 ras Proteins