The isoprostane 8-iso-PGF(2alpha) stimulates endothelial cells to bind monocytes: differences from thromboxane-mediated endothelial activation.

15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid/pharmacology Cell Adhesion/physiology Cells, Cultured Cyclic AMP-Dependent Protein Kinases/metabolism Dinoprost/analogs & derivatives,pharmacology E-Selectin/metabolism Endothelium, Vascular/cytology,metabolism F2-Isoprostanes Humans MAP Kinase Signaling System/physiology Models, Biological Monocytes/metabolism NF-kappa B/metabolism Protein Kinase C/metabolism Receptors, Thromboxane/antagonists & inhibitors Thromboxanes/metabolism Vascular Cell Adhesion Molecule-1/metabolism Vasoconstrictor Agents/pharmacology

E-Selectin F2-Isoprostanes NF-kappa B Receptors, Thromboxane Thromboxanes Vascular Cell Adhesion Molecule-1 Vasoconstrictor Agents 8-epi-prostaglandin F2alpha 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid Dinoprost Cyclic AMP-Dependent Protein Kinases Protein Kinase C