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PMID: 11402012 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Distribution of quorum-sensing genes in the Burkholderia cepacia complex.

Infection and immunity ·Vol. 69 ·No. 7 ·2001-07-00 ·Pages 4661-6

Lutter E, Lewenza S, Dennis JJ, Visser MB, Sokol PA

Abstract

The distribution of quorum-sensing genes among strains from seven genomovars of the Burkholderia cepacia complex was examined by PCR. cepR and cepI were amplified from B. cepacia genomovars I and III, B. stabilis, and B. vietnamiensis. cepR was also amplified from B. multivorans and B. cepacia genomovar VI. bviIR were amplified from B. vietnamiensis. All genomovars produced N-octanoyl-L-homoserine lactone and N-hexanoyl-L-homoserine lactone. B. vietnamiensis and B. cepacia genomovar VII produced additional N-acyl-L-homoserine lactones.

MeSH Terms
4-Butyrolactone/analogs & derivatives,biosynthesis Amino Acid Sequence Bacterial Proteins/genetics Base Sequence Burkholderia/genetics Burkholderia cepacia/genetics Genes, Bacterial Homoserine/analogs & derivatives,biosynthesis Lactones Ligases Molecular Sequence Data Sequence Homology, Amino Acid
Chemicals
Bacterial Proteins CepR protein, Burkholderia Lactones N-hexanoyl-L-homoserine lactone N-octanoylhomoserine lactone homoserine lactone Homoserine Ligases N-acylhomoserine lactone synthase 4-Butyrolactone
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Lutter E
Department of Microbiology and Infectious Diseases, University of Calgary Health Sciences Center, Calgary, Alberta, Canada T2N 4N1.
Lewenza S
Dennis J J
Visser M B
Sokol P A
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Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/IAI.69.7.4661-4666.2001
Published
2001-07-00
Pages
4661-6
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC98545
Subset
IM
Databases
GENBANK
AF296284, AF333002, AF333003, AF333004, AF333005, AF333006, AF333007, AF333008, AF337814
External Links
PubMed source DOI: 10.1128/IAI.69.7.4661-4666.2001 PMC Full Text View journal details
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