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PMID: 114107 Published · ppublish English Comparative Study Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Activity of beta-lactam antibiotics against Pseudomonas aeruginosa carrying R plasmids determining different beta-lactamases.

Antimicrobial agents and chemotherapy ·Vol. 16 ·No. 2 ·1979-08-00 ·Pages 243-5

Jacoby GA, Sutton L

Abstract

Azlocillin, carbenicillin, cefsulodin, mezlocillin, nocardicin A, piperacillin, pirbenicillin, sulbenicillin, and ticarcillin, but not HR756, showed reduced activity against Pseudomonas aeruginosa strains producing seven types of beta-lactamase.

MeSH Terms

Microbial Sensitivity Tests Penicillins/pharmacology Pseudomonas aeruginosa/drug effects R Factors/drug effects Species Specificity beta-Lactamases/genetics

Chemicals

Penicillins beta-Lactamases

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Jacoby G A

Sutton L

References (16)

16 references, click to expand

beta-lactamase stability of HR 756, a novel cephalosporin, compared to that of cefuroxime and cefoxitin.
Antimicrob Agents Chemother. 1978 Sep;14(3):322-6 PMID: 101128
Analytical isoelectric focusing of R factor-determined beta-lactamases: correlation with plasmid compatibility.
J Bacteriol. 1976 Feb;125(2):713-8 PMID: 1107329
Comparative in vitro activity and clinical pharmacology of ticarcillin and carbenicillin.
Antimicrob Agents Chemother. 1975 Oct;8(4):457-62 PMID: 1190752
Properties of R plasmids determining gentamicin resistance by acetylation in Pseudomonas aeruginosa.
Antimicrob Agents Chemother. 1974 Sep;6(3):239-52 PMID: 15830469
Acquisition by Escherichia coli of plasmid-borne beta-lactamases normally confined to Pseudomonas spp.
Plasmid. 1979 Apr;2(2):269-78 PMID: 377324
Plasmid-mediated penicillin beta-lactamases in Pseudomonas aeruginosa.
Antimicrob Agents Chemother. 1976 Jan;9(1):55-60 PMID: 4010
R factors, beta-lactamase, and carbenicillin-resistant Pseudomonas aeruginosa.
Lancet. 1971 Aug 14;2(7720):342-4 PMID: 4105047
Properties of the beta-lactamase specified by the Pseudomonas plasmid RPL11.
J Bacteriol. 1977 Oct;132(1):341-5 PMID: 410783
SCE-129, antipseudomonal cephalosporin: in vitro and in vivo antibacterial activities.
Antimicrob Agents Chemother. 1978 Feb;13(2):137-45 PMID: 417670
Sensitivity of Pseudomonas aeruginosa to antibiotics: emergence of strains highly resistant to carbenicillin.
Lancet. 1969 Aug 30;2(7618):448-52 PMID: 4183901
HR 756, a new cephalosporin active against gram-positive and gram-negative aerobic and anaerobic bacteria.
Antimicrob Agents Chemother. 1979 Feb;15(2):273-81 PMID: 426518
Cephalosporinase and penicillinase activities of a beta-lactamase from Pseudomonas pyocyanea.
Biochem J. 1965 Sep;96(3):739-52 PMID: 5862414
Azlocillin and mezlocillin: new ureido penicillins.
Antimicrob Agents Chemother. 1978 Jun;13(6):930-8 PMID: 677860
The beta-lactamases of gram-negative bacteria and their role in resistance to beta-lactam antibiotics.
J Antimicrob Chemother. 1976 Jun;2(2):115-57 PMID: 783110
In vitro and in vivo antibacterial activity of T-1220, a new semisynthetic penicillin.
Antimicrob Agents Chemother. 1977 Oct;12(4):455-60 PMID: 921239
Nocardicin A, a new monocyclic beta-lactam antibiotic. I. Discovery, isolation and characterization.
J Antibiot (Tokyo). 1976 May;29(5):492-500 PMID: 956036

Article Info

Journal

Antimicrobial agents and chemotherapy

Abbr.

Antimicrob Agents Chemother

ISSN

0066-4804

DOI

10.1128/AAC.16.2.243

Published

1979-08-00

Pages

243-5

Language

English

Region

United States

NLM ID

0315061

PMCID

PMC352832

Subset

External Links

PubMed source DOI: 10.1128/AAC.16.2.243 PMC Full Text View journal details

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Activity of beta-lactam antibiotics against Pseudomonas aeruginosa carrying R plasmids determining different beta-lactamases.

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