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PMID: 11433367 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

The bacterial toxin toolkit.

Nature reviews. Molecular cell biology ·Vol. 2 ·No. 7 ·2001-07-00 ·Pages 530-7

Schiavo G, van der Goot FG

Abstract

Pathogenic bacteria and higher eukaryotes have spent a long time together, leading to a precise understanding of one another's way of functioning. Through rapid evolution, bacteria have engineered increasingly sophisticated weapons to hit exactly where it hurts, interfering with fundamental host functions. However, toxins are not only useful to the bacteria - they have also become an essential asset for life scientists, who can now use them as toolkits to explore cellular processes.

MeSH Terms
Bacterial Toxins/chemistry,metabolism,pharmacology Cell Adhesion Cell Membrane/physiology Cell Polarity Cytoskeleton/drug effects,metabolism Endocytosis/drug effects,physiology Membrane Fusion Protein Transport Signal Transduction/drug effects,physiology Two-Hybrid System Techniques
Chemicals
Bacterial Toxins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Schiavo G
Imperial Cancer Research Fund, 44 Lincoln's Inn Fields, London WC2A 3PX, UK. [email protected]
van der Goot F G
Article Info
Journal
Nature reviews. Molecular cell biology
Abbr.
Nat Rev Mol Cell Biol
ISSN
1471-0072
Published
2001-07-00
Pages
530-7
Language
English
Region
England
NLM ID
100962782
Subset
IM
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