Vascular endothelial growth factor triggers signaling cascades mediating multiple myeloma cell growth and migration.

Cell Division/drug effects Cell Movement/drug effects Endothelial Growth Factors/genetics,metabolism,pharmacology Extracellular Matrix Proteins/analysis,genetics,metabolism Flavonoids/pharmacology Gene Expression Humans Leukemia, Plasma Cell/metabolism,pathology Lymphokines/genetics,metabolism,pharmacology MAP Kinase Kinase 1 MAP Kinase Kinase Kinases/metabolism Mitogen-Activated Protein Kinase Kinases/antagonists & inhibitors Mitogen-Activated Protein Kinases/metabolism Multiple Myeloma/metabolism,pathology Protein Kinase C/metabolism Protein Serine-Threonine Kinases/antagonists & inhibitors Proto-Oncogene Proteins c-raf/metabolism Reverse Transcriptase Polymerase Chain Reaction Signal Transduction Tumor Cells, Cultured Vascular Endothelial Growth Factor A Vascular Endothelial Growth Factors

Endothelial Growth Factors Extracellular Matrix Proteins Flavonoids Lymphokines Vascular Endothelial Growth Factor A Vascular Endothelial Growth Factors Protein Serine-Threonine Kinases Proto-Oncogene Proteins c-raf Protein Kinase C Mitogen-Activated Protein Kinases MAP Kinase Kinase Kinases MAP Kinase Kinase 1 MAP2K1 protein, human Mitogen-Activated Protein Kinase Kinases 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one