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PMID: 1145185 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Genetic linkage between the HL-A system and a deficit of the second component (C2) of complement.

Science (New York, N.Y.) ·Vol. 188 ·No. 4192 ·1975-06-06 ·Pages 1020-2

Wolski KP, Schmid FR, Mittal KK

Abstract

From a family of 14 individuals, evidence was obtained suggesting linkage between the HL-A haplotypes and the transmission of a 50 percent deficit in the functional activity of the C2 component of complement.

MeSH Terms
Adolescent Adult Aged Alleles Complement C2/deficiency Complement System Proteins/deficiency Female Genetic Linkage HLA Antigens Heterozygote Histocompatibility Antigens Homozygote Humans Male Middle Aged Pedigree
Chemicals
Complement C2 HLA Antigens Histocompatibility Antigens Complement System Proteins
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Wolski K P
Schmid F R
Mittal K K
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
DOI
10.1126/science.1145185
Published
1975-06-06
Pages
1020-2
Language
English
Region
United States
NLM ID
0404511
Subset
IM
External Links
PubMed source DOI: 10.1126/science.1145185 View journal details
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