Home LiteratureArticle Details
PMID: 11479621 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S. Review

Autoimmune disease: why and where it occurs.

Nature medicine ·Vol. 7 ·No. 8 ·2001-08-00 ·Pages 899-905

Marrack P, Kappler J, Kotzin BL

Abstract

Autoimmune disease is controlled by genetic and environmental factors. Both of these affect susceptibility to autoimmunity at three levels: the overall reactivity of the immune system, the specific antigen and its presentation, and the target issue.

MeSH Terms
Antigens/immunology Autoimmune Diseases/etiology,genetics,immunology Chromosome Mapping Cross Reactions Humans Models, Biological
Chemicals
Antigens
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Marrack P
Howard Hughes Medical Institute, University of Colorado Health Sciences Center, Denver, Colorado, USA. [email protected]
Kappler J
Kotzin B L
Article Info
Journal
Nature medicine
Abbr.
Nat Med
ISSN
1078-8956
DOI
10.1038/90935
Email
[email protected]
Published
2001-08-00
Pages
899-905
Language
English
Region
United States
NLM ID
9502015
Subset
IM
Grants
NIAID NIH HHS · AI-17134 · United States
NIAID NIH HHS · AI-18785 · United States
NIAID NIH HHS · AI-22295 · United States
NIAMS NIH HHS · AR-37070 · United States
External Links
PubMed source DOI: 10.1038/90935 View journal details
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