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PMID: 1148362 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

The receptor for tetrodotoxin and saxitoxin. A structural hypothesis.

Biophysical journal ·Vol. 15 ·No. 6 ·1975-06-00 ·Pages 615-9

Hille B

Abstract

暂无摘要

MeSH Terms

Binding Sites Models, Chemical Molecular Conformation Receptors, Drug Saxitoxin Tetrodotoxin

Chemicals

Receptors, Drug Saxitoxin Tetrodotoxin

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Hille B

References (11)

11 references, click to expand

Biochemical studies on paralytic shellfish poisons.
Ann N Y Acad Sci. 1960 Nov 17;90:843-55 PMID: 13747257
The rate of action of tetrodotoxin on myelinated nerve fibres of Xenopus laevis and Rana esculenta.
J Physiol. 1973 Aug;233(1):167-94 PMID: 4543328
Tetrodotoxin, saxitoxin, and related substances: their applications in neurobiology.
Int Rev Neurobiol. 1972;15:83-166 PMID: 4347729
Tetrodotoxin derivatives: chemical structure and blockage of nerve membrane conductance.
Science. 1967 May 19;156(3777):976-9 PMID: 6023268
Potency difference between the zwitterion form and the cation forms of tetrodotoxin.
Science. 1967 Jun 23;156(3782):1625-7 PMID: 6025123
Evidence that tetrodotoxin and saxitoxin act at a metal cation binding site in the sodium channels of nerve membrane.
Proc Natl Acad Sci U S A. 1974 Oct;71(10):3936-40 PMID: 4530274
Pharmacological modifications of the sodium channels of frog nerve.
J Gen Physiol. 1968 Feb;51(2):199-219 PMID: 5641635
Letter: The structure of saxitoxin.
J Am Chem Soc. 1975 Mar 5;97(5):1238 PMID: 1133383
Tetrodotoxin, saxitoxin and their significance in the study of excitation phenomena.
Pharmacol Rev. 1966 Jun;18(2):997-1049 PMID: 5328391
The permeability of the sodium channel to organic cations in myelinated nerve.
J Gen Physiol. 1971 Dec;58(6):599-619 PMID: 5315827
Comparison of tetrodotoxin and procaine in internally perfused squid giant axons.
J Gen Physiol. 1967 May;50(5):1413-28 PMID: 6033593

Article Info

Journal

Biophysical journal

Abbr.

Biophys J

ISSN

0006-3495

DOI

Published

1975-06-00

Pages

615-9

Language

English

Region

United States

NLM ID

0370626

PMCID

PMC1334742

Subset

External Links

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