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PMID: 1154025 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Muscle activation: effects of small length changes on calcium release in single fibers.

Science (New York, N.Y.) ·Vol. 189 ·No. 4206 ·1975-09-12 ·Pages 881-4

Ridgeway EB, Gordon AM

Abstract

In single muscle fibers, small (1 percent) changes of length have a marked effect of both the calcium activation and the tension elicited by a constant current stimulus. The decrease in tension with shortening is accounted for almost entirely by a decrease in calcium release, rather than by changes in mechanical factors, such as filament geometry.

MeSH Terms
Aequorin Animals Calcium/metabolism Evoked Potentials In Vitro Techniques Membrane Potentials Muscle Contraction Muscles/anatomy & histology,metabolism Structure-Activity Relationship Thoracica Time Factors
Chemicals
Aequorin Calcium
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Ridgeway E B
Gordon A M
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
DOI
10.1126/science.1154025
Published
1975-09-12
Pages
881-4
Language
English
Region
United States
NLM ID
0404511
Subset
IM
External Links
PubMed source DOI: 10.1126/science.1154025 View journal details
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