Home LiteratureArticle Details
PMID: 11544183 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Plant growth homeostasis is controlled by the Arabidopsis BON1 and BAP1 genes.

Genes & development ·Vol. 15 ·No. 17 ·2001-09-01 ·Pages 2263-72

Hua J, Grisafi P, Cheng SH, Fink GR

Abstract

Wild-type Arabidopsis plants maintain a relatively constant size over a wide range of temperatures. Here we show that this homeostasis requires the BONZAI1 (BON1) gene because bon1 null mutants make miniature fertile plants at 22 degrees C but have wild-type appearance at 28 degrees C. The expression of BON1 and a BON1-associated protein (BAP1) is modulated by temperature. Thus BON1 and BAP1 may have a direct role in regulating cell expansion and cell division at lower temperatures. BON1 contains a Ca(2+)-dependent phospholipid-binding domain and is associated with the plasma membrane. It belongs to the copine gene family, which is conserved from protozoa to humans. Our data suggest that this gene family may function in the pathway of membrane trafficking in response to external conditions.

MeSH Terms
Animals Arabidopsis/genetics Arabidopsis Proteins Blotting, Western Calcium/metabolism Calcium-Binding Proteins Carrier Proteins/genetics,physiology Cell Division Cell Membrane/metabolism Cloning, Molecular Gene Expression Regulation, Plant Genes, Plant Growth Substances Humans Membrane Proteins/genetics,physiology Microscopy, Confocal Models, Genetic Molecular Sequence Data Multigene Family Mutation Phospholipids/metabolism Plant Physiological Phenomena Plant Proteins/genetics,physiology Protein Binding Subcellular Fractions/metabolism Temperature Two-Hybrid System Techniques
Chemicals
Arabidopsis Proteins BON1 protein, Arabidopsis BON1-associated protein, Arabidopsis Calcium-Binding Proteins Carrier Proteins Growth Substances Membrane Proteins Phospholipids Plant Proteins Calcium
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Hua J
Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA.
Grisafi P
Cheng S H
Fink G R
References (24)
24 references, click to expand
  1. The yeast A kinases differentially regulate iron uptake and respiratory function.
    Proc Natl Acad Sci U S A. 2000 May 23;97(11):5984-8 PMID: 10811893
  2. Genetic control of size in Drosophila.
    Philos Trans R Soc Lond B Biol Sci. 2000 Jul 29;355(1399):945-52 PMID: 11128988
  3. Membrane fusion and exocytosis.
    Annu Rev Biochem. 1999;68:863-911 PMID: 10872468
  4. Isolation of mutations affecting the development of freezing tolerance in Arabidopsis thaliana (L.) Heynh.
    Plant Physiol. 1996 Aug;111(4):1011-9 PMID: 8756493
  5. Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana.
    Plant J. 1998 Dec;16(6):735-43 PMID: 10069079
  6. Activation tagging in Arabidopsis.
    Plant Physiol. 2000 Apr;122(4):1003-13 PMID: 10759496
  7. Analysis of the H(+)-ATPase and other proteins of the Arabidopsis plasma membrane.
    Methods Cell Biol. 1995;50:129-48 PMID: 8531789
  8. PLANT COLD ACCLIMATION: Freezing Tolerance Genes and Regulatory Mechanisms.
    Annu Rev Plant Physiol Plant Mol Biol. 1999 Jun;50:571-599 PMID: 15012220
  9. Engineered GFP as a vital reporter in plants.
    Curr Biol. 1996 Mar 1;6(3):325-30 PMID: 8805250
  10. Ca2+/phospholipid-binding (C2) domain in multiple plant proteins: novel components of the calcium-sensing apparatus.
    Plant Mol Biol. 1998 Mar;36(5):627-37 PMID: 9526495
  11. Localization and subcellular distribution of N-copine in mouse brain.
    J Neurochem. 1999 Jan;72(1):373-9 PMID: 9886090
  12. Transient transformation of Arabidopsis leaf protoplasts: a versatile experimental system to study gene expression.
    Plant J. 1994 Mar;5(3):421-7 PMID: 8180625
  13. Characterization of human copine III as a phosphoprotein with associated kinase activity.
    Biochemistry. 2000 Oct 24;39(42):13034-43 PMID: 11041869
  14. Sterol methyltransferase 1 controls the level of cholesterol in plants.
    Plant Cell. 2000 Jun;12(6):853-70 PMID: 10852933
  15. Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast.
    Genetics. 1996 Dec;144(4):1425-36 PMID: 8978031
  16. Erv41p and Erv46p: new components of COPII vesicles involved in transport between the ER and Golgi complex.
    J Cell Biol. 2001 Feb 5;152(3):503-18 PMID: 11157978
  17. N-copine: a novel two C2-domain-containing protein with neuronal activity-regulated expression.
    FEBS Lett. 1998 May 22;428(1-2):80-4 PMID: 9645480
  18. Improved binary vectors for Agrobacterium-mediated plant transformation.
    Plant Mol Biol. 1990 Feb;14(2):269-76 PMID: 1966276
  19. The copines, a novel class of C2 domain-containing, calcium-dependent, phospholipid-binding proteins conserved from Paramecium to humans.
    J Biol Chem. 1998 Jan 16;273(3):1393-402 PMID: 9430674
  20. C2-domains, structure and function of a universal Ca2+-binding domain.
    J Biol Chem. 1998 Jun 26;273(26):15879-82 PMID: 9632630
  21. Expression of endoxyloglucan transferase genes in acaulis mutants of Arabidopsis.
    Plant Physiol. 1999 Nov;121(3):715-22 PMID: 10557219
  22. Yeast homologues of tomosyn and lethal giant larvae function in exocytosis and are associated with the plasma membrane SNARE, Sec9.
    J Cell Biol. 1999 Jul 12;146(1):125-40 PMID: 10402465
  23. SNAREpins: minimal machinery for membrane fusion.
    Cell. 1998 Mar 20;92(6):759-72 PMID: 9529252
  24. Ca2+, annexins, and GTP modulate exocytosis from maize root cap protoplasts
    Plant Cell. 1998 Aug;10(8):1267-76 PMID: 9707528
Article Info
Journal
Genes & development
Abbr.
Genes Dev
ISSN
0890-9369
DOI
10.1101/gad.918101
Published
2001-09-01
Pages
2263-72
Language
English
Region
United States
NLM ID
8711660
PMCID
PMC312777
Subset
IM
Databases
GENBANK
AY045764, AY045765
External Links
PubMed source DOI: 10.1101/gad.918101 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2