Mechanis of chlorampenicol-cephalordine synergism on Enerobacteiaeae.

Antimicrobial agents and chemotherapy ·Vol. 7 ·No. 6 ·1975-06-00 ·Pages 845-9

Michel J, Bornstein H, Luboshitzky R, Sacks T

Abstract

A synergistic in vitro bactericidal effect of combinations of chloramphenicol and beta-lactams on strains of Enterobacteriaceae is described. The synergism is seen with strains which are resistant to the beta-lactam and is due to chloramphenicol-induced inhibition of beta-lactamase production.

MeSH Terms

Cephaloridine/pharmacology Chloramphenicol/pharmacology Drug Synergism Enterobacteriaceae/drug effects

Chemicals

Chloramphenicol Cephaloridine

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Michel J

Bornstein H

Luboshitzky R

Sacks T

References (15)

15 references, click to expand

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Article Info

Journal

Antimicrobial agents and chemotherapy

Abbr.

Antimicrob Agents Chemother

ISSN

0066-4804

DOI

10.1128/AAC.7.6.845

Published

1975-06-00

Pages

845-9

Language

English

Region

United States

NLM ID

0315061

PMCID

PMC429238

Subset

External Links

PubMed source DOI: 10.1128/AAC.7.6.845 PMC Full Text View journal details

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Mechanis of chlorampenicol-cephalordine synergism on Enerobacteiaeae.

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