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PMID: 1159798 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Triple helices formed by polyuridylic acid with some adenosine derivatives.

Journal of molecular evolution ·Vol. 5 ·No. 2 ·1975-07-11 ·Pages 117-23

Shim JL, Lohrmann R, Orgel LE

Abstract

We have prepared a variety of derivatives of adenosine which, at neutral pH's, carry protonated amine functions. These derivatives form stable helical structures with polyuridylic acid, but the melting points are not substantially higher than those of helical complexes formed by adenosine derivatives lacking cationic groups.

MeSH Terms
Adenosine/analogs & derivatives Adenosine Monophosphate/analogs & derivatives Diamines/chemical synthesis Nucleic Acid Conformation Poly U
Chemicals
Diamines Poly U Adenosine Monophosphate Adenosine
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Shim J L
Lohrmann R
Orgel L E
References (7)
7 references, click to expand
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    Science. 1968 Jul 26;161(3839):387 PMID: 5661298
  4. The general synthetic route to amino acid esters of nucleotides and nucleoside-5'-triphosphates and some properties of these compounds.
    Tetrahedron. 1970 Sep;26(18):4419-33 PMID: 5469480
  5. On the possible role of crystals in the origins of life. VII. The adsorption and polymerization of phosphoramidates by montmorillonite clay.
    J Mol Evol. 1974;3(2):141-50 PMID: 4407469
  6. Synthesis of some nucleotide anhydrides.
    Biochemistry. 1962 Nov;1:1171-4 PMID: 13935532
  7. Catalysts for the polymerization of adenosine cyclic 2',3'-phosphate on a poly (U) template.
    Biochim Biophys Acta. 1971 Jul 29;240(4):463-71 PMID: 4330816
Article Info
Journal
Journal of molecular evolution
Abbr.
J Mol Evol
ISSN
0022-2844
DOI
10.1007/BF01732516
Published
1975-07-11
Pages
117-23
Language
English
Region
Germany
NLM ID
0360051
Subset
IM
External Links
PubMed source DOI: 10.1007/BF01732516 View journal details
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