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PMID: 11607533 Published · ppublish English Journal Article

Biosynthesis and metabolism of salicylic acid.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 92 ·No. 10 ·1995-05-09 ·Pages 4076-9

Lee HI, León J, Raskin I

Abstract

Pathways of salicylic acid (SA) biosynthesis and metabolism in tobacco have been recently identified. SA, an endogenous regulator of disease resistance, is a product of phenylpropanoid metabolism formed via decarboxylation of trans-cinnamic acid to benzoic acid and its subsequent 2-hydroxylation to SA. In tobacco mosaic virus-inoculated tobacco leaves, newly synthesized SA is rapidly metabolized to SA O-beta-D-glucoside and methyl salicylate. Two key enzymes involved in SA biosynthesis and metabolism: benzoic acid 2-hydroxylase, which converts benzoic acid to SA, and UDPglucose:SA glucosyltransferase (EC 2.4.1.35), which catalyzes conversion of SA to SA glucoside have been partially purified and characterized. Progress in enzymology and molecular biology of SA biosynthesis and metabolism will provide a better understanding of signal transduction pathway involved in plant disease resistance.

Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Lee H I
AgBiotech Center, Cook College, Rutgers University, New Brunswick, NJ 08903-0231, USA.
León J
Raskin I
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Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.92.10.4076
Published
1995-05-09
Pages
4076-9
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC41889
External Links
PubMed source DOI: 10.1073/pnas.92.10.4076 PMC Full Text View journal details
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