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PMID: 1163537 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Polymorphism of human alpha fucosidase.

American journal of human genetics ·Vol. 27 ·No. 5 ·1975-09-00 ·Pages 651-61

Turner BM, Turner VS, Beratis NG, Hirschhorn K

Abstract

A common polymorphism of human alpha fucosidase has been detected by the technique of isoelectric focusing on thin layer acrylamide gel. Family studies have shown that the three common phenotypes Fu 1, Fu 2, and Fu 2-1 represent homozygosity or heterozygosity for two autosomal codominat alleles, Fu1 and Fu2. Frequencies of the Fu1 and Fu2 alleles in the New York populations studied were .753 and .247 among whites and .926 and .074 among blacks, respectively.

MeSH Terms
Alleles Blacks Brain/enzymology Disaccharidases/analysis Female Genes, Dominant Humans Isoelectric Point Kidney/enzymology Leukocytes/enzymology Liver/enzymology Lung/enzymology Male Muscles/enzymology Pedigree Polymorphism, Genetic Spleen/enzymology Whites alpha-L-Fucosidase/analysis
Chemicals
Disaccharidases alpha-L-Fucosidase
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Turner B M
Turner V S
Beratis N G
Hirschhorn K
References (8)
8 references, click to expand
  1. Protein measurement with the Folin phenol reagent.
    J Biol Chem. 1951 Nov;193(1):265-75 PMID: 14907713
  2. Salivary and pancreatic amylase: electrophoretic characterizations and genetic studies.
    Am J Hum Genet. 1973 Sep;25(5):510-22 PMID: 4741846
  3. Linkage analysis using somatic cell hybrids.
    Adv Hum Genet. 1972;30:173-235 PMID: 4125882
  4. Mucopolysaccharidosis by absence of alpha-fucosidase.
    Lancet. 1968 Jun 1;1(7553):1198 PMID: 4172303
  5. Isozymes of human alpha-L-fucosidase detectable by starch gel electrophoresis.
    Clin Chim Acta. 1974 Nov 20;57(1):29-35 PMID: 4371999
  6. Fucosidosis.
    J Pediatr. 1969 Oct;75(4):665-74 PMID: 4241464
  7. Electrophoretic forms of human liver alpha-L-fucosidase and their relationship to fucosidosis (mucopolysaccharidosis F).
    Clin Chim Acta. 1974 Dec 17;57(3):307-13 PMID: 4215602
  8. Caucasian genes in American Negroes.
    Science. 1969 Aug 22;165(3895):762-8 PMID: 4894336
Article Info
Journal
American journal of human genetics
Abbr.
Am J Hum Genet
ISSN
0002-9297
Published
1975-09-00
Pages
651-61
Language
English
Region
United States
NLM ID
0370475
PMCID
PMC1762838
Subset
IM
External Links
PubMed source PMC Full Text View journal details
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