An increase of C'3 fraction, already observed in Hodgkin's disease has been confirmed, and is here described in a group of 33 patients at various clinical stages of Hodgkin's disease. It is consistently higher than those found in a group of 26 normal subjects. Conglutinins present in Hodgkin's disease patients, as far as their behaviour is concerned, may be considered as immunoconglutinins (I-K).
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