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PMID: 1168171 Published · ppublish English Journal Article

Effect of administered human interferon on experimental rabies in monkeys.

Infection and immunity ·Vol. 11 ·No. 5 ·1975-05-00 ·Pages 1156-8

Hilfenhaus J, Karges HE, Weinmann E, Barth R

Abstract

Cynomolgus monkeys infected with rabies virus were protected by repeated intramuscular administration of human leukocyte interferon beginning 24 h after infection.

MeSH Terms
Animals Humans Injections, Intramuscular Injections, Intravenous Interferons/administration & dosage,therapeutic use Leukocytes/immunology Macaca fascicularis Rabies/drug therapy Rabies virus/immunology Semliki forest virus Virus Replication/drug effects
Chemicals
Interferons
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Hilfenhaus J
Karges H E
Weinmann E
Barth R
References (7)
7 references, click to expand
  1. Role of interferon induction in the protective activity of rabies vaccines.
    J Infect Dis. 1972 Oct;126(4):408-18 PMID: 4561726
  2. Laboratory techniques in rabies: the fluorescent antibody test.
    Monogr Ser World Health Organ. 1973;(23):73-84 PMID: 4219510
  3. Growth inhibition of human lymphoblastoid cells by interferon preparations, obtained from human leukocytes.
    Z Naturforsch C. 1974 Sep-Oct;29C(9-10):618-22 PMID: 4278116
  4. Protection of rabbits against experimental rabies of poly I-poly C.
    Nature. 1970 Apr 11;226(5241):171-2 PMID: 4314319
  5. Rabies in rabbits and mice: protective effect of polyriboinosinic-polyribocytidylic acid.
    J Infect Dis. 1972 Apr;125(4):345-52 PMID: 4553077
  6. Interferon administered in the cerebrospinal space and its effect on rabies in rabbits.
    Infect Immun. 1974 Feb;9(2):286-93 PMID: 4816460
  7. The kinetics of human interferon clearance in gibbons.
    Proc Soc Exp Biol Med. 1973 Mar;142(3):946-7 PMID: 4692028
Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/iai.11.5.1156-1158.1975
Published
1975-05-00
Pages
1156-8
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC415191
Subset
IM
External Links
PubMed source DOI: 10.1128/iai.11.5.1156-1158.1975 PMC Full Text View journal details
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