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PMID: 11715049 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

The ETS-domain transcription factor family.

Nature reviews. Molecular cell biology ·Vol. 2 ·No. 11 ·2001-11-00 ·Pages 827-37

Sharrocks AD

Abstract

ETS-domain transcription-factor networks represent a model for how combinatorial gene expression is achieved. These transcription factors interact with a multitude of co-regulatory partners to elicit gene-specific responses and drive distinct biological processes. These proteins are controlled by a complex series of inter and intramolecular interactions, and signalling pathways impinge on these proteins to further regulate their action.

MeSH Terms
Animals DNA/metabolism Humans Models, Biological Models, Molecular Multigene Family Neoplasms/metabolism Phosphorylation Protein Binding Protein Structure, Tertiary Proto-Oncogene Proteins/physiology Proto-Oncogene Proteins c-ets Transcription Factors/physiology
Chemicals
Proto-Oncogene Proteins Proto-Oncogene Proteins c-ets Transcription Factors DNA
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Sharrocks A D
School of Biological Sciences, University of Manchester, 2.205 Stopford Building, Oxford Road, Manchester, M13 9PT, UK. [email protected]
Article Info
Journal
Nature reviews. Molecular cell biology
Abbr.
Nat Rev Mol Cell Biol
ISSN
1471-0072
Published
2001-11-00
Pages
827-37
Language
English
Region
England
NLM ID
100962782
Subset
IM
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