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PMID: 11724736 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Nucleosome formation potential of exons, introns, and Alu repeats.

Bioinformatics (Oxford, England) ·Vol. 17 ·No. 11 ·2001-11-00 ·Pages 1062-4

Levitsky VG, Podkolodnaya OA, Kolchanov NA, Podkolodny NL

Abstract

A program for constructing nucleosome formation potential profile was applied for investigation of exons, introns, and repetitive sequences. The program is available at http://wwwmgs.bionet.nsc.ru/mgs/programs/recon/. We have demonstrated that introns and repetitive sequences exhibit higher nucleosome formation potentials than exons. This fact may be explained by functional saturation of exons with genetic code, hindering the localization of efficient nucleosome positioning sites.

MeSH Terms
Alu Elements Computational Biology Databases, Nucleic Acid Exons Humans Introns Nucleosomes/genetics Software
Chemicals
Nucleosomes
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Levitsky V G
Laboratory of Theoretical Genetics, Institute of Cytology & Genetics, 630090, Lavrentiev ave. 10, Novosibirsk, Russia.
Podkolodnaya O A
Kolchanov N A
Podkolodny N L
Article Info
Journal
Bioinformatics (Oxford, England)
Abbr.
Bioinformatics
ISSN
1367-4803
Published
2001-11-00
Pages
1062-4
Language
English
Region
England
NLM ID
9808944
Subset
IM
Analysis Services
Analysis Services

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