Drinking patterns and alcohol-related birth defects.

Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism ·Vol. 25 ·No. 3 ·2001-00-00 ·Pages 168-74

Maier SE, West JR

Abstract

The consequences of maternal alcohol use during pregnancy on the outcome of offspring depend, among other factors, on the amount and pattern of alcohol consumption. Animal studies found that bingelike drinking patterns, in which the fetus is exposed to high blood alcohol concentrations (BACs) over relatively short periods of time, are particularly harmful, even if the overall alcohol amount consumed is less than those of more continuous drinking patterns. Long-term studies in humans have confirmed that children of binge-drinking mothers exhibited especially severe cognitive and behavioral deficits. Binge drinking may be particularly harmful because it results in high BACs, may occur during critical periods of brain development, and may be associated with repeated withdrawal episodes.

MeSH Terms

Abnormalities, Drug-Induced/blood,etiology Alcohol Drinking/adverse effects Alcoholism/complications Animals Brain/abnormalities,drug effects,growth & development Disease Models, Animal Ethanol/blood,poisoning Female Humans Maternal Behavior Pregnancy Prenatal Exposure Delayed Effects Rats

Chemicals

Ethanol

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Maier S E

Department of Human Anatomy and Medical Neurobiology, College of Medicine, Texas A&M University System Health Science Center, College Station, Texas, USA.

West J R

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Article Info

Journal

Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism

Abbr.

Alcohol Res Health

ISSN

1535-7414

Published

2001-00-00

Pages

168-74

Language

English

Region

United States

NLM ID

100900708

PMCID

PMC6707176

Subset

External Links

PubMed source PMC Full Text View journal details

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Drinking patterns and alcohol-related birth defects.

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