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PMID: 11861612 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Review

T cell memory.

Annual review of immunology ·Vol. 20 ·2002-00-00 ·Pages 551-79

Sprent J, Surh CD

Abstract

Typical immune responses lead to prominent clonal expansion of antigen-specific T and B cells followed by differentiation into effector cells. Most effector cells die at the end of the immune response but some of these cells survive and form long-lived memory cells. The factors controlling the formation and survival of memory T cells are reviewed.

MeSH Terms

Adjuvants, Immunologic/metabolism Animals Antigen-Presenting Cells/immunology Antigens/metabolism Apoptosis Cell Differentiation Cell Division Cell Movement Cytokines/metabolism Homeostasis Humans Immunologic Memory Lymphocyte Activation T-Lymphocytes/cytology,immunology

Chemicals

Adjuvants, Immunologic Antigens Cytokines

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Sprent Jonathan

Department of Immunology, IMM4, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037, USA. [email protected]

Surh Charles D

Article Info

Journal

Annual review of immunology

Abbr.

Annu Rev Immunol

ISSN

0732-0582

DOI

10.1146/annurev.immunol.20.100101.151926

[email protected]

Published

2002-00-00

Epub

2001-00-04

Pages

551-79

Language

English

Region

United States

NLM ID

8309206

Subset

Grants

NIA NIH HHS · AG01743 · United States

NIAID NIH HHS · AI21487 · United States

NIAID NIH HHS · AI41079 · United States

NIAID NIH HHS · AI45809 · United States

NIAID NIH HHS · AI46710 · United States

NCI NIH HHS · CA38355 · United States

External Links

PubMed source DOI: 10.1146/annurev.immunol.20.100101.151926 View journal details

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