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PMID: 11888686 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S. Review

Mechanisms of pathogenesis in herpetic immunoinflammatory ocular lesions.

Veterinary microbiology ·Vol. 86 ·No. 1-2 ·2002-04-22 ·Pages 17-26

Deshpande SP, Zheng M, Lee S, Rouse BT

Abstract

This article reviews possible mechanisms by which ocular infections with herpes simplex virus result in a blinding immunoinflammatory lesion in the cornea. We conclude that this immunoinflammatory response involves multiple immune mechanisms including autoimmunity.

MeSH Terms
Animals Autoimmunity/immunology Humans Keratitis, Herpetic/immunology,pathology,virology Mice Mice, Inbred BALB C Mice, SCID Mice, Transgenic Simplexvirus/immunology,pathogenicity
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Deshpande Shilpa P
Department of Microbiology, University of Tennessee, M409, Walter Life Sciences Building, Knoxville, TN 37996-0845, USA.
Zheng Mei
Lee Sujin
Rouse Barry T
Article Info
Journal
Veterinary microbiology
Abbr.
Vet Microbiol
ISSN
0378-1135
DOI
10.1016/s0378-1135(01)00487-4
Published
2002-04-22
Pages
17-26
Language
English
Region
Netherlands
NLM ID
7705469
Subset
IM
Grants
NEI NIH HHS · EY05093 · United States
External Links
PubMed source DOI: 10.1016/s0378-1135(01)00487-4 View journal details
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