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Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells.
Nature. 1996 Jul 11;382(6587):171-4
PMID: 8700208
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Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses.
Cell. 1998 May 29;93(5):841-50
PMID: 9630227
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Serine phosphorylation of STATs.
Oncogene. 2000 May 15;19(21):2628-37
PMID: 10851062
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A Stat3-interacting protein (StIP1) regulates cytokine signal transduction.
Proc Natl Acad Sci U S A. 2000 Aug 29;97(18):10120-5
PMID: 10954736
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STAT proteins and transcriptional responses to extracellular signals.
Trends Biochem Sci. 2000 Oct;25(10):496-502
PMID: 11050435
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Nuclear export signal located within theDNA-binding domain of the STAT1transcription factor.
EMBO J. 2000 Nov 15;19(22):6196-206
PMID: 11080165
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Partial impairment of cytokine responses in Tyk2-deficient mice.
Immunity. 2000 Oct;13(4):549-60
PMID: 11070173
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Tyk2 plays a restricted role in IFN alpha signaling, although it is required for IL-12-mediated T cell function.
Immunity. 2000 Oct;13(4):561-71
PMID: 11070174
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Immune response in Stat2 knockout mice.
Immunity. 2000 Dec;13(6):795-804
PMID: 11163195
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Structure of the mouse Stat 3/5 locus: evolution from Drosophila to zebrafish to mouse.
Genomics. 2001 Jan 15;71(2):150-5
PMID: 11161808
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Stat5a is mandatory for adult mammary gland development and lactogenesis.
Genes Dev. 1997 Jan 15;11(2):179-86
PMID: 9009201
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Three-dimensional structure of the Stat3beta homodimer bound to DNA.
Nature. 1998 Jul 9;394(6689):145-51
PMID: 9671298
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Erythropoietin receptor activation by a ligand-induced conformation change.
Science. 1999 Feb 12;283(5404):990-3
PMID: 9974393
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Negative regulators of cytokine signaling.
Int J Hematol. 2001 Apr;73(3):292-8
PMID: 11345194
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PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies.
Genes Dev. 2001 Dec 1;15(23):3088-103
PMID: 11731474
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Stat proteins and oncogenesis.
J Clin Invest. 2002 May;109(9):1139-42
PMID: 11994401
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What does Stat3 do?
J Clin Invest. 2002 May;109(9):1143-8
PMID: 11994402
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Molecular aspects of primary immunodeficiencies: lessons from cytokine and other signaling pathways.
J Clin Invest. 2002 May;109(10):1261-9
PMID: 12021239
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IFNs and STATs in innate immunity to microorganisms.
J Clin Invest. 2002 May;109(10):1271-7
PMID: 12021240
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JAK-STAT signaling in asthma.
J Clin Invest. 2002 May;109(10):1279-83
PMID: 12021241
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Signaling through the JAK/STAT pathway, recent advances and future challenges.
Gene. 2002 Feb 20;285(1-2):1-24
PMID: 12039028
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Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3.
Science. 1995 Nov 3;270(5237):794-7
PMID: 7481767
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Defective lymphoid development in mice lacking Jak3.
Science. 1995 Nov 3;270(5237):800-2
PMID: 7481769
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Developmental defects of lymphoid cells in Jak3 kinase-deficient mice.
Immunity. 1995 Dec;3(6):771-82
PMID: 8777722
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Essential role of Stat6 in IL-4 signalling.
Nature. 1996 Apr 18;380(6575):627-30
PMID: 8602263
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Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene.
Nature. 1996 Apr 18;380(6575):630-3
PMID: 8602264
-
Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway.
Cell. 1996 Feb 9;84(3):431-42
PMID: 8608597
-
Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease.
Cell. 1996 Feb 9;84(3):443-50
PMID: 8608598
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Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.
Immunity. 1996 Mar;4(3):313-9
PMID: 8624821
-
Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice.
Nature. 1996 Jul 11;382(6587):174-7
PMID: 8700209
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The Stat family in cytokine signaling.
Curr Opin Cell Biol. 2001 Apr;13(2):211-7
PMID: 11248555
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GAS elements: a few nucleotides with a major impact on cytokine-induced gene expression.
J Interferon Cytokine Res. 1997 Mar;17(3):121-34
PMID: 9085936
-
Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression.
Proc Natl Acad Sci U S A. 1997 Jul 8;94(14):7239-44
PMID: 9207075
-
Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases.
Science. 1997 Nov 28;278(5343):1630-2
PMID: 9374464
-
Structure of the amino-terminal protein interaction domain of STAT-4.
Science. 1998 Feb 13;279(5353):1048-52
PMID: 9461439
-
Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses.
Cell. 1998 May 1;93(3):373-83
PMID: 9590172
-
Jak2 is essential for signaling through a variety of cytokine receptors.
Cell. 1998 May 1;93(3):385-95
PMID: 9590173
-
Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis.
Cell. 1998 May 1;93(3):397-409
PMID: 9590174
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Jaks and STATs: biological implications.
Annu Rev Immunol. 1998;16:293-322
PMID: 9597132
-
Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA.
Cell. 1998 May 29;93(5):827-39
PMID: 9630226
-
A small amphipathic alpha-helical region is required for transcriptional activities and proteasome-dependent turnover of the tyrosine-phosphorylated Stat5.
EMBO J. 2000 Feb 1;19(3):392-9
PMID: 10654938