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PMID: 12023934 Published · ppublish English Comment Editorial

Short-term regulation of PDE4 activity.

British journal of pharmacology ·Vol. 136 ·No. 3 ·2002-06-00 ·Pages 339-40

Manganiello V

Abstract

暂无摘要

MeSH Terms
3',5'-Cyclic-AMP Phosphodiesterases/chemistry,genetics,metabolism Animals Catalytic Domain Cyclic AMP/metabolism Cyclic GMP/metabolism Cyclic Nucleotide Phosphodiesterases, Type 4 Gene Expression Regulation Humans Isoenzymes/chemistry,genetics,metabolism
Chemicals
Isoenzymes Cyclic AMP 3',5'-Cyclic-AMP Phosphodiesterases Cyclic Nucleotide Phosphodiesterases, Type 4 Cyclic GMP
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Manganiello V
PCCMB, NHLB1, NIH, Bldg 10, Room 5N307, 9000 Rockville Pike, Belhesda, Maryland, MD 20892, USA. [email protected]
References (10)
10 references, click to expand
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  2. mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module.
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  4. Cyclic nucleotide phosphodiesterases and their role in endocrine cell signaling.
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  5. Long PDE4 cAMP specific phosphodiesterases are activated by protein kinase A-mediated phosphorylation of a single serine residue in Upstream Conserved Region 1 (UCR1).
    Br J Pharmacol. 2002 Jun;136(3):421-33 PMID: 12023945
  6. A family of human phosphodiesterases homologous to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs.
    Mol Cell Biol. 1993 Oct;13(10):6558-71 PMID: 8413254
  7. Phosphodiesterase isozymes: molecular targets for novel antiasthma agents.
    Am J Respir Crit Care Med. 1998 Feb;157(2):351-70 PMID: 9476844
  8. The multienzyme PDE4 cyclic adenosine monophosphate-specific phosphodiesterase family: intracellular targeting, regulation, and selective inhibition by compounds exerting anti-inflammatory and antidepressant actions.
    Adv Pharmacol. 1998;44:225-342 PMID: 9547887
  9. Activation of the cAMP-specific phosphodiesterase PDE4D3 by phosphorylation. Identification and function of an inhibitory domain.
    J Biol Chem. 1999 Jul 9;274(28):19677-85 PMID: 10391907
  10. The molecular biology of cyclic nucleotide phosphodiesterases.
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Article Info
Journal
British journal of pharmacology
Abbr.
Br J Pharmacol
ISSN
0007-1188
DOI
10.1038/sj.bjp.0704741
Email
[email protected]
Published
2002-06-00
Pages
339-40
Language
English
Region
England
NLM ID
7502536
PMCID
PMC1573368
Subset
IM
Corrections
CommentOn
PMID: 12023945
External Links
PubMed source DOI: 10.1038/sj.bjp.0704741 PMC Full Text View journal details
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