Home LiteratureArticle Details
PMID: 12045250 Published · ppublish English Journal Article Review

Making eosinophils through subtle shifts in transcription factor expression.

The Journal of experimental medicine ·Vol. 195 ·No. 11 ·2002-06-03 ·Pages F43-7

McNagny K, Graf T

Abstract

暂无摘要

MeSH Terms
Animals Antigens, CD34/metabolism CCAAT-Enhancer-Binding Protein-alpha/biosynthesis,genetics,metabolism Cell Differentiation DNA-Binding Proteins/biosynthesis,genetics,metabolism Eosinophils/cytology,metabolism Erythroid-Specific DNA-Binding Factors Gene Expression Regulation Humans Stem Cells/cytology,metabolism Transcription Factors/biosynthesis,genetics,metabolism
Chemicals
Antigens, CD34 CCAAT-Enhancer-Binding Protein-alpha DNA-Binding Proteins Erythroid-Specific DNA-Binding Factors Transcription Factors
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
McNagny Kelly
The Biomedical Research Centre, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
Graf Thomas
References (25)
25 references, click to expand
  1. Hematopoietic development: a balancing act.
    Curr Opin Genet Dev. 2001 Oct;11(5):513-9 PMID: 11532392
  2. Antagonism between C/EBPbeta and FOG in eosinophil lineage commitment of multipotent hematopoietic progenitors.
    Genes Dev. 2000 Oct 1;14(19):2515-25 PMID: 11018018
  3. Differentiation plasticity of hematopoietic cells.
    Blood. 2002 May 1;99(9):3089-101 PMID: 11964270
  4. Avian models to study the transcriptional control of hematopoietic lineage commitment and to identify lineage-specific genes.
    Cells Tissues Organs. 2002;171(1):44-63 PMID: 12021491
  5. Essential and instructive roles of GATA factors in eosinophil development.
    J Exp Med. 2002 Jun 3;195(11):1379-86 PMID: 12045236
  6. Targeted deletion of a high-affinity GATA-binding site in the GATA-1 promoter leads to selective loss of the eosinophil lineage in vivo.
    J Exp Med. 2002 Jun 3;195(11):1387-95 PMID: 12045237
  7. Chicken "erythroid" cells transformed by the Gag-Myb-Ets-encoding E26 leukemia virus are multipotent.
    Cell. 1992 Jul 24;70(2):201-13 PMID: 1322247
  8. GATA-1 reprograms avian myelomonocytic cell lines into eosinophils, thromboblasts, and erythroblasts.
    Genes Dev. 1995 May 15;9(10):1250-62 PMID: 7758949
  9. CD34: structure, biology, and clinical utility.
    Blood. 1996 Jan 1;87(1):1-13 PMID: 8547630
  10. NF-M (chicken C/EBP beta) induces eosinophilic differentiation and apoptosis in a hematopoietic progenitor cell line.
    EMBO J. 1995 Dec 15;14(24):6127-35 PMID: 8557032
  11. The eosinophil-specific cell surface antigen, EOS47, is a chicken homologue of the oncofetal antigen melanotransferrin.
    Blood. 1996 Feb 15;87(4):1343-52 PMID: 8608223
  12. Lineage commitment of transformed haematopoietic progenitors is determined by the level of PKC activity.
    EMBO J. 1996 Apr 15;15(8):1894-901 PMID: 8617236
  13. Acute avian leukemia viruses as tools to study hematopoietic cell differentiation.
    Curr Top Microbiol Immunol. 1996;212:143-62 PMID: 8934817
  14. Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice.
    Proc Natl Acad Sci U S A. 1997 Jan 21;94(2):569-74 PMID: 9012825
  15. Transcription factor GATA-2 is required for proliferation/survival of early hematopoietic cells and mast cell formation, but not for erythroid and myeloid terminal differentiation.
    Blood. 1997 May 15;89(10):3636-43 PMID: 9160668
  16. Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG.
    Genes Dev. 1998 Apr 15;12(8):1176-88 PMID: 9553047
  17. Mechanisms of transcription in eosinophils: GATA-1, but not GATA-2, transactivates the promoter of the eosinophil granule major basic protein gene.
    Blood. 1998 May 1;91(9):3447-58 PMID: 9558404
  18. Eosinophilia.
    N Engl J Med. 1998 May 28;338(22):1592-600 PMID: 9603798
  19. Regulation of eosinophil-specific gene expression by a C/EBP-Ets complex and GATA-1.
    EMBO J. 1998 Jul 1;17(13):3669-80 PMID: 9649437
  20. Loops, lineage, and leukemia.
    Cell. 1998 Jul 10;94(1):9-12 PMID: 9674421
  21. PU.1 induces myeloid lineage commitment in multipotent hematopoietic progenitors.
    Genes Dev. 1998 Aug 1;12(15):2403-12 PMID: 9694804
  22. Distinct C/EBP functions are required for eosinophil lineage commitment and maturation.
    Genes Dev. 1998 Aug 1;12(15):2413-23 PMID: 9694805
  23. C/EBPbeta and GATA-1 synergistically regulate activity of the eosinophil granule major basic protein promoter: implication for C/EBPbeta activity in eosinophil gene expression.
    Blood. 1999 Aug 15;94(4):1429-39 PMID: 10438731
  24. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages.
    Nature. 2000 Mar 9;404(6774):193-7 PMID: 10724173
  25. Reciprocal roles for CCAAT/enhancer binding protein (C/EBP) and PU.1 transcription factors in Langerhans cell commitment.
    J Exp Med. 2002 Mar 4;195(5):547-58 PMID: 11877478
Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
Published
2002-06-03
Pages
F43-7
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2193544
Subset
IM
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]