Ornithine decarboxylase activity and: [125I]iododeoxyuridine incorporation in rat prostate.

The Biochemical journal ·Vol. 150 ·No. 3 ·1975-09-00 ·Pages 557-9

Fuller DJ, Donaldson LJ, Thomas GH

Abstract

The relationship between ornithine decarboxylase activity and [125I]iododexyuridine incorporation was studied in prostates from castrated rats (aged 5, 26 and 80 weeks) injected daily with testosterone for up to 10 days. The results suggest that ornithine decarboxylase activity is a parameter of secretory activity, rather than growth, in the ventral prostate. In the dorsolateral prostate, ornithine decarboxylase activity tends to parallel [125I]iododeoxyuridine incorporation.

MeSH Terms

Animals Carboxy-Lyases/metabolism Castration DNA/biosynthesis Idoxuridine/metabolism Male Ornithine Decarboxylase/metabolism Prostate/enzymology,metabolism Rats Testosterone/pharmacology

Chemicals

Testosterone DNA Carboxy-Lyases Ornithine Decarboxylase Idoxuridine

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Fuller D J

Donaldson L J

Thomas G H

References (13)

13 references, click to expand

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Differences in proliferative activity of rat and human prostate in culture.
Br J Cancer. 1975 May;31(5):570-80 PMID: 50856
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Article Info

Journal

The Biochemical journal

Abbr.

Biochem J

ISSN

0264-6021

DOI

10.1042/bj1500557

Published

1975-09-00

Pages

557-9

Language

English

Region

England

NLM ID

2984726R

PMCID

PMC1165771

Subset

External Links

PubMed source DOI: 10.1042/bj1500557 PMC Full Text View journal details

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Ornithine decarboxylase activity and: [125I]iododeoxyuridine incorporation in rat prostate.

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