[Further studies of prostaglandin, the physically active substance of certain genital glands].

Weitere Untersuchungen ueber Prostaglandin, die physiologisch aktive Substanz gewisser Genitaldruesen.

Skandinavisches Archiv fur Physiologie ·Vol. 81 ·1939-00-00 ·Pages 65-80

Von Euler US

Abstract

暂无摘要

Keywords

Animals Laboratory Biology Clinical Research Endocrine System Physiology Prostaglandins--side effects Research Methodology

MeSH Terms

Animals, Laboratory Biology Endocrine System Physiology Prostaglandins Research

Chemicals

Prostaglandins

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Von Euler U S

Other Abstracts

eng

Prostaglandins were extracted from the prostate gland and testicles of sheep in the form of a barium salt and were used in experiments on rabbits and cats. Intravenous injection of prostaglandins caused a decrease in blood pressure

this effect was reduced or absent after hepatic blood vessels were cut off or after the animal had been eviscerated. Intravenous injection or injection into the v. portae caused an increase in the portal blood pressure and a decrease in the right anterior ventricle. No significant effects of prostaglandin on heart-lung preparations were observed. Perfusion of the lung with prostaglandin caused vasoconstriction. Prostaglandin perfusion of the posterior end caused vasodilatation, which was not as marked in the case of the cats. Perfusion of the kidney caused vasoconstriction in cats and vasodilatation in rabbits. A latency period was observed between intraarterial prostaglandin injection and its effects

this period was longer than for other substances with vasodilatory effect. Prostaglandin injections can counteract vasoconstriction caused by adrenalin

prostaglandin was also shown to counteract the effect of adrenalin in the uterus of rabbits.

Article Info

Journal

Skandinavisches Archiv fur Physiologie

Abbr.

Skand Arch Physiol

Published

1939-00-00

Pages

65-80

Language

ger

Region

Germany

NLM ID

20740590R

External Links

PubMed source

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[Further studies of prostaglandin, the physically active substance of certain genital glands].

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