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PMID: 12391309 Published · ppublish English Journal Article Review Comment

A copper connection to the uptake of platinum anticancer drugs.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 99 ·No. 22 ·2002-10-29 ·Pages 13963-5

Nitiss JL

Abstract

暂无摘要

MeSH Terms
Adenosine Triphosphatases/metabolism Animals Antineoplastic Agents/metabolism,pharmacology Cation Transport Proteins Ceruloplasmin/genetics,metabolism Cisplatin/metabolism,pharmacology Copper/metabolism Copper Transporter 1 Fungal Proteins/genetics,metabolism Humans Membrane Proteins/genetics,metabolism Molecular Chaperones/genetics,metabolism Nuclear Proteins/genetics,metabolism Platinum/metabolism Saccharomyces cerevisiae/drug effects,genetics,metabolism Saccharomyces cerevisiae Proteins Superoxide Dismutase/genetics,metabolism Superoxide Dismutase-1 Transcription Factors/genetics,metabolism
Chemicals
Antineoplastic Agents CTR1 protein, S cerevisiae Cation Transport Proteins Copper Transporter 1 Fungal Proteins MAC1 protein, S cerevisiae Membrane Proteins Molecular Chaperones Nuclear Proteins SLC31A1 protein, human SOD1 protein, human Saccharomyces cerevisiae Proteins Transcription Factors Platinum Copper LYS7 protein, S cerevisiae Superoxide Dismutase Superoxide Dismutase-1 Ceruloplasmin FET3 protein, S cerevisiae Adenosine Triphosphatases Cisplatin
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Nitiss John L
Molecular Pharmacology Department, St. Jude Children's Research Hospital, 332 North Lauderdale, Memphis, TN 38105, USA. [email protected]
References (27)
27 references, click to expand
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Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.232574299
Email
[email protected]
Published
2002-10-29
Epub
2002-00-21
Pages
13963-5
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC137818
Subset
IM
Grants
NCI NIH HHS · P30 CA021765 · United States
NCI NIH HHS · R01 CA052814 · United States
NCI NIH HHS · R01 CA082313 · United States
Corrections
CommentOn
PMID: 12370430
External Links
PubMed source DOI: 10.1073/pnas.232574299 PMC Full Text View journal details
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