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PMID: 12421291 Published · ppublish English Letter

Aspergillus nidulans is frequently resistant to amphotericin B.

Mycoses ·Vol. 45 ·No. 9-10 ·2002-11-00 ·Pages 406-7

Kontoyiannis DP, Lewis RE, May GS, Osherov N, Rinaldi MG

Abstract

The high failure rate of amphotericin B-based therapy in patients with Aspergillus nidulans infections may not be entirely a result of host factors as suggested previously. Innate resistance of A. nidulans to polyenes may contribute to the poor response in patients.

MeSH Terms
Amphotericin B/pharmacology,therapeutic use Antifungal Agents/pharmacology,therapeutic use Aspergillosis/drug therapy,microbiology Aspergillus nidulans/drug effects,isolation & purification Drug Resistance, Microbial Humans Microbial Sensitivity Tests Treatment Outcome
Chemicals
Antifungal Agents Amphotericin B
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Kontoyiannis D P
Lewis R E
May G S
Osherov N
Rinaldi M G
Article Info
Journal
Mycoses
Abbr.
Mycoses
ISSN
0933-7407
DOI
10.1046/j.1439-0507.2002.00797.x
Published
2002-11-00
Pages
406-7
Language
English
Region
Germany
NLM ID
8805008
Subset
IM
External Links
PubMed source DOI: 10.1046/j.1439-0507.2002.00797.x View journal details
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