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PMID: 12446907 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Genetic evidence for an East Asian origin of domestic dogs.

Science (New York, N.Y.) ·Vol. 298 ·No. 5598 ·2002-11-22 ·Pages 1610-3

Savolainen P, Zhang YP, Luo J, Lundeberg J, Leitner T

Abstract

The origin of the domestic dog from wolves has been established, but the number of founding events, as well as where and when these occurred, is not known. To address these questions, we examined the mitochondrial DNA (mtDNA) sequence variation among 654 domestic dogs representing all major dog populations worldwide. Although our data indicate several maternal origins from wolf, >95% of all sequences belonged to three phylogenetic groups universally represented at similar frequencies, suggesting a common origin from a single gene pool for all dog populations. A larger genetic variation in East Asia than in other regions and the pattern of phylogeographic variation suggest an East Asian origin for the domestic dog, approximately 15,000 years ago.

MeSH Terms

Animals Animals, Domestic/anatomy & histology,classification,genetics Archaeology Asia DNA, Mitochondrial/genetics Dogs/anatomy & histology,classification,genetics Female Gene Pool Genes Genetic Variation Haplotypes Molecular Sequence Data Phylogeny Time Wolves/genetics

Chemicals

DNA, Mitochondrial

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Savolainen Peter

Department of Biotechnology, Royal Institute of Technology (KTH), 10691 Stockholm, Sweden. [email protected]

Zhang Ya-ping

Luo Jing

Lundeberg Joakim

Leitner Thomas

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

1095-9203

DOI

10.1126/science.1073906

[email protected]

Published

2002-11-22

Pages

1610-3

Language

English

Region

United States

NLM ID

0404511

Subset

Databases

GENBANK

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Corrections

CommentIn

PMID: 12446885

CommentIn

PMID: 12634800

External Links

PubMed source DOI: 10.1126/science.1073906 View journal details

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Genetic evidence for an East Asian origin of domestic dogs.

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