Biosynthesis of the modified nucleoside Q in transfer RNA.

Nucleic acids research ·Vol. 3 ·No. 2 ·1976-02-00 ·Pages 393-8

Kuchino Y, Kasai H, Nihei K, Nishimura S

Abstract

During biosynthesis of the modified nucleoside Q, 7-(4,5-DIHYDROXYL-1-1-CYCLOPENTEN-3-YL-AMINOMETHYL)-7-DEAZAGUANOSINE, IN TRNA, the carbon atom at position 8 in precursor molecule guanine was expelled together with the nitrogen atom N-7 in a fashion similar to that in the biosynthesis of the nucleoside antibiotic toyocamycin.

MeSH Terms

Chromatography, Thin Layer Guanosine/analogs & derivatives,metabolism Mutation RNA, Transfer/metabolism

Chemicals

Guanosine RNA, Transfer

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Kuchino Y

Kasai H

Nihei K

Nishimura S

References (8)

8 references, click to expand

Structure of the modified nucleoside Q isolated from Escherichia coli transfer ribonucleic acid. 7-(4,5-cis-Dihydroxy-1-cyclopenten-3-ylaminomethyl)-7-deazaguanosine.
Biochemistry. 1975 Sep 23;14(19):4198-208 PMID: 1101947
Distribution of the modified nucleoside Q and its derivatives in animal and plant transfer RNA's.
Nucleic Acids Res. 1975 Oct;2(10):1931-9 PMID: 1187350
The nucleotide sequences of tyrosine transfer RNAs of Escherichia coli.
Eur J Biochem. 1970 Apr;13(3):461-83 PMID: 4315419
Histidine regulation in Salmonella typhimurium. 13. Nucleotide sequence of histidine transfer ribonucleic acid.
J Biol Chem. 1972 May 25;247(10):2989-3000 PMID: 4337503
Minor components in transfer RNA: their characterization, location, and function.
Prog Nucleic Acid Res Mol Biol. 1972;12:49-85 PMID: 4557059
Genetic and biochemical studies of the guanosine 5'-monophosphate pathway in Escherichia coli.
Biochim Biophys Acta. 1967 Aug 22;145(1):31-40 PMID: 4861262
Purification of histidine-specific transfer RNA from yeast.
Biochim Biophys Acta. 1967;145(3):605-12 PMID: 4863903
Biosynthesis of the pyrrolopyrimidine nucleoside antibiotic, toyocamycin. VII. Origin of the pyrrole carbons and the cyano carbon.
J Biol Chem. 1970 Sep 10;245(17):4365-71 PMID: 5498424

Article Info

Journal

Nucleic acids research

Abbr.

Nucleic Acids Res

ISSN

0305-1048

DOI

10.1093/nar/3.2.393

Published

1976-02-00

Pages

393-8

Language

English

Region

England

NLM ID

0411011

PMCID

PMC342909

Subset

External Links

PubMed source DOI: 10.1093/nar/3.2.393 PMC Full Text View journal details

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