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PMID: 12618465 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

The membrane domain of SpoIIIE is required for membrane fusion during Bacillus subtilis sporulation.

Journal of bacteriology ·Vol. 185 ·No. 6 ·2003-03-00 ·Pages 2005-8

Sharp MD, Pogliano K

Abstract

During Bacillus subtilis sporulation, SpoIIIE is required for both postseptational chromosome segregation and membrane fusion after engulfment. Here we demonstrate that SpoIIIE must be present in the mother cell to promote membrane fusion and that the N-terminal membrane-spanning segments constitute a minimal membrane fusion domain, as well as direct septal localization.

MeSH Terms
Bacillus subtilis/chemistry,cytology,physiology Bacterial Proteins/chemistry,genetics,metabolism Cell Division DNA, Bacterial/metabolism Membrane Fusion/physiology Mutation Spores, Bacterial/physiology
Chemicals
Bacterial Proteins DNA, Bacterial spore-specific proteins, Bacillus
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Sharp Marc D
Division of Biological Sciences, University of California, San Diego, La Jolla, California 92093-0349, USA.
Pogliano Kit
References (15)
15 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/JB.185.6.2005-2008.2003
Published
2003-03-00
Pages
2005-8
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC150122
Subset
IM
Grants
NIGMS NIH HHS · R01 GM057045 · United States
NIGMS NIH HHS · GM57045 · United States
External Links
PubMed source DOI: 10.1128/JB.185.6.2005-2008.2003 PMC Full Text View journal details
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